| Gene Symbol |
KCNA7
|
| Entrez Gene |
3743
|
| Alt Symbol |
HAK6, KV1.7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, voltage gated shaker related subfamily A, member 7
|
| Other Description |
potassium voltage-gated channel subfamily A member 7|potassium voltage-gated channel, shaker-related subfamily, member 7|voltage-dependent potassium channel Kv1.7|voltage-gated potassium channel KCNA7|voltage-gated potassium channel subunit Kv1.7
|
| Swissprots |
A1KYX7 Q96RP8 Q9BYS4
|
| Accessions |
EAW52444 Q96RP8 AF315818 AAK63002 AJ310479 CAC29065 AY779768 AAX11186 BC140906 AAI40907 NM_031886 NP_114092
|
| Function |
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in skeletal muscle, heart and kidney. {ECO:0000269|PubMed:11368907, ECO:0000269|PubMed:11896454}.
|
![Western Blot: KCNA7 Overexpression Lysate (Adult Normal) [NBL1-12140] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KCNA7.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8013_KCNA7%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12140-img0002.jpg)