Gene Symbol | KCNA7 |
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Entrez Gene | 3743 |
Alt Symbol | HAK6, KV1.7 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated shaker related subfamily A, member 7 |
Other Description | potassium voltage-gated channel subfamily A member 7|potassium voltage-gated channel, shaker-related subfamily, member 7|voltage-dependent potassium channel Kv1.7|voltage-gated potassium channel KCNA7|voltage-gated potassium channel subunit Kv1.7 |
Swissprots | A1KYX7 Q96RP8 Q9BYS4 |
Accessions | EAW52444 Q96RP8 AF315818 AAK63002 AJ310479 CAC29065 AY779768 AAX11186 BC140906 AAI40907 NM_031886 NP_114092 |
Function | Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Highly expressed in skeletal muscle, heart and kidney. {ECO:0000269|PubMed:11368907, ECO:0000269|PubMed:11896454}. |
KV1.7 CRISPR/Cas9 KO Plasmid (h) - sc-408744 from Santa Cruz Biotechnology
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KV1.7 HDR Plasmid (h) - sc-408744-HDR from Santa Cruz Biotechnology
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KV1.7 Double Nickase Plasmid (h) - sc-408744-NIC from Santa Cruz Biotechnology
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KV1.7 Double Nickase Plasmid (h2) - sc-408744-NIC-2 from Santa Cruz Biotechnology
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KV1.7 CRISPR Activation Plasmid (h) - sc-408744-ACT from Santa Cruz Biotechnology
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KV1.7 CRISPR Activation Plasmid (h2) - sc-408744-ACT-2 from Santa Cruz Biotechnology
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KV1.7 Lentiviral Activation Particles (h) - sc-408744-LAC from Santa Cruz Biotechnology
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KV1.7 Lentiviral Activation Particles (h2) - sc-408744-LAC-2 from Santa Cruz Biotechnology
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KV1.7 siRNA (h) - sc-97461 from Santa Cruz Biotechnology
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KV1.7 shRNA Plasmid (h) - sc-97461-SH from Santa Cruz Biotechnology
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KV1.7 shRNA (h) Lentiviral Particles - sc-97461-V from Santa Cruz Biotechnology
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KCNA7 RNAi - H00003743-R01 from Novus Biologicals
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MISSION® esiRNA - EHU040831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10921 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11628 from Sigma-Aldrich
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KCNA7 siRNA (Human) - CRH2519 from Cohesion Biosciences
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KCNA7, siRNA - MBS8240165 from MyBioSource
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shRNA set against Human KCNA7 (NM_031886.2) - SHH322759 from Creative biogene
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shRNA set against Human KCNA7(NM_031886.2) - SHL188222 from Creative biogene
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Human KCNA7 siRNA - orb263021 from Biorbyt
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KCNA7 shRNA Plasmid (Human) - CHH2519 from Cohesion Biosciences
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KCNA7 miRNA 3'UTR clone - MiUTR1H-05095 from Creative biogene
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