| Gene Symbol |
SPESP1
|
| Entrez Gene |
246777
|
| Alt Symbol |
ESP, SP-ESP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sperm equatorial segment protein 1
|
| Other Description |
equatorial segment protein|glycosylated 38 kDa sperm protein C-7/8
|
| Swissprots |
Q8WVH8 Q6UW49 Q8NG22
|
| Accessions |
EAW77829 Q6UW49 AF275321 AAM69364 AY358983 AAQ89342 BC017998 AAH17998 BG720873 BM564110 HQ447748 ADQ32233 NM_145658 NP_663633
|
| Subcellular Location |
Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:12773409}. Note=Small proacrosomal granules (during the Golgi phase), enlarged acrosomal vesicles (during the cap phase), acrosome (during the elongating phase), equatorial segment of the acrosome (during the maturation phase).
|
| Tissue Specificity |
Highly expressed in testis, where it is localized in the acrosome of postmeiotic stages of spermiogenesis (round and elongating spermatids and in ejaculated spermatozoa) (at protein level). Poorly expressed in placenta and fetal lung. {ECO:0000269|PubMed:12773409}.
|
![Western Blot: SPESP1 Overexpression Lysate (Adult Normal) [NBL1-16393] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SPESP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6699_SPESP1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16393-img0002.jpg)