Gene Symbol | SPESP1 |
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Entrez Gene | 246777 |
Alt Symbol | ESP, SP-ESP |
Species | Human |
Gene Type | protein-coding |
Description | sperm equatorial segment protein 1 |
Other Description | equatorial segment protein|glycosylated 38 kDa sperm protein C-7/8 |
Swissprots | Q8WVH8 Q6UW49 Q8NG22 |
Accessions | EAW77829 Q6UW49 AF275321 AAM69364 AY358983 AAQ89342 BC017998 AAH17998 BG720873 BM564110 HQ447748 ADQ32233 NM_145658 NP_663633 |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:12773409}. Note=Small proacrosomal granules (during the Golgi phase), enlarged acrosomal vesicles (during the cap phase), acrosome (during the elongating phase), equatorial segment of the acrosome (during the maturation phase). |
Tissue Specificity | Highly expressed in testis, where it is localized in the acrosome of postmeiotic stages of spermiogenesis (round and elongating spermatids and in ejaculated spermatozoa) (at protein level). Poorly expressed in placenta and fetal lung. {ECO:0000269|PubMed:12773409}. |
SPESP1 CRISPR/Cas9 KO Plasmid (h) - sc-415176 from Santa Cruz Biotechnology
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SPESP1 HDR Plasmid (h) - sc-415176-HDR from Santa Cruz Biotechnology
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SPESP1 Double Nickase Plasmid (h) - sc-415176-NIC from Santa Cruz Biotechnology
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SPESP1 Double Nickase Plasmid (h2) - sc-415176-NIC-2 from Santa Cruz Biotechnology
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SPESP1 CRISPR Activation Plasmid (h) - sc-415176-ACT from Santa Cruz Biotechnology
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SPESP1 CRISPR Activation Plasmid (h2) - sc-415176-ACT-2 from Santa Cruz Biotechnology
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SPESP1 Lentiviral Activation Particles (h) - sc-415176-LAC from Santa Cruz Biotechnology
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SPESP1 Lentiviral Activation Particles (h2) - sc-415176-LAC-2 from Santa Cruz Biotechnology
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SPESP1 siRNA (h) - sc-90095 from Santa Cruz Biotechnology
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SPESP1 shRNA Plasmid (h) - sc-90095-SH from Santa Cruz Biotechnology
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SPESP1 shRNA (h) Lentiviral Particles - sc-90095-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU031691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20460 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20460 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01878 from Sigma-Aldrich
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SPESP1 siRNA (Human) - CRJ6626 from Cohesion Biosciences
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SPESP1 - MBS8238585 from MyBioSource
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shRNA set against Human SPESP1 (NM_145658.3) - SHH416540 from Creative biogene
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SPESP1 shRNA Plasmid (Human) - CHJ6626 from Cohesion Biosciences
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SPESP1 miRNA 3'UTR clone - MiUTR3H-10586 from Creative biogene
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