PEX5

Gene Symbol PEX5
Entrez Gene 5830
Alt Symbol PBD2A, PBD2B, PTS1-BP, PTS1R, PXR1
Species Human
Gene Type protein-coding
Description peroxisomal biogenesis factor 5
Other Description PTS1 receptor|peroxin-5|peroxisomal C-terminal targeting signal import receptor|peroxisomal targeting signal 1 (SKL type) receptor|peroxisomal targeting signal 1 receptor|peroxisomal targeting signal import receptor|peroxisomal targeting signal receptor 1|peroxisome receptor 1
Swissprots B4DZ45 P50542 D3DUT8 Q15266 A8K891 Q15115 B7ZAD5 Q96FN7
Accessions AAC50344 EAW88670 EAW88671 EAW88672 EAW88673 EAW88674 EAW88675 P50542 AI252784 AK225126 AK292256 BAF84945 AK299105 BAG61162 AK299534 BAG61481 AK301700 BAG63172 AK302742 BAG63957 AK303515 BAG64544 AK312317 AK316250 BAH14621 BC010621 AAH10621 DA399480 DQ600153 DQ891142 ABM82068 DQ894321 ABM85247 U19721 AAC50103 X84899 CAA59324 Z48054 CAA88131 XM_005253455 XP_005253512 XM_011520793 XP_011519095 XM_011520794 XP_011519096 XM_011520795 XP_011519097 XM_011520796 XP_011519098 XM_011520797 XP_011519099 XM_011520798 XP_011519100 XM_011520799 XP_011519101 XM_011520800 XP_011519102 XM_011520801 XP_011519103 XM_011520802 XP_011519104 NM_000319 NP_000310 NM_001131023 NP_001124495 NM_001131024 NP_001124496 NM_001131025 NP_001124497 NM_001131026 NP_001124498 NM_001300789 NP_001287718
Function Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. {ECO:0000269|PubMed:7706321, ECO:0000269|PubMed:7719337, ECO:0000269|PubMed:7790377}.
Subcellular Location Cytoplasm. Peroxisome membrane; Peripheral membrane protein. Note=Its distribution appears to be dynamic. It is probably a cycling receptor found mainly in the cytoplasm and as well associated to the peroxisomal membrane through a docking factor (PEX13).
Tissue Specificity Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:7706321, ECO:0000269|PubMed:7719337, ECO:0000269|PubMed:7790377}.
Top Pathways Peroxisome

Peroxin 5 (B-9) - sc-365629 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Peroxin 5 (B-9): sc-365629. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Peroxin 5 (E-8) - sc-390294 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Peroxin 5 (E-8): sc-390294. Western blot analysis of Peroxin 5 expression in SK-BR-3 (A) and SHP-77 (B) whole cell lysates.

Peroxin 5 (F-10) - sc-365983 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Peroxin 5 (F-10): sc-365983. Western blot analysis of Peroxin 5 expression in non-transfected: sc-117752 (A) and human Peroxin 5 transfected: sc-173622 (B) 293T whole cell lysates.

Peroxin 5 (B-3) - sc-137103 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Peroxin 5 (B-3): sc-137103. Western blot analysis of Peroxin 5 expression in non-transfected: sc-110760 (A) and mouse Peroxin 5 transfected: sc-110710 (B) 293 whole cell lysates.

Peroxin 5 (F-9) - sc-137135 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Peroxin 5 (F-9): sc-137135. Western blot analysis of Peroxin 5 expression in non-transfected: sc-110760 (A) and mouse Peroxin 5 transfected: sc-110710 (B) 293 whole cell lysates.

Peroxin 5 (G-20) - sc-23190 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Peroxin 5 (G-20): sc-23190. Western blot analysis of Peroxin 5 expression in HeLa whole cell lysate.

Peroxin 5 (V-20) - sc-23188 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Peroxin 5 (V-20): sc-23188. Western blot analysis of Peroxin 5 expression in non-transfected: sc-110760 (A) and mouse Peroxin 5 transfected: sc-110710 (B) 293 whole cell lysates.

Peroxin 5 (H-292) - sc-366127 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Peroxin 5 (H-292): sc-366127. Western blot analysis of Peroxin 5 expression in non-transfected: sc-110760 (A) and mouse Peroxin 5 transfected: sc-110710 (B) 293 whole cell lysates.

Anti-PEX5 antibody - ab192322 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PEX5 antibody - ab126086 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab126086, at 1/500, staining PEX5 in Paraffin-embedded Human U87 xenograft tissue by Immunohistochemistry.

Anti-PEX5 Antibody - LS-C341867 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PEX5 Antibody (C-Terminus) - LS-C111800 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PEX5 antibody LS-C111800 Western blot of COLO205 cell lysate.

Anti-PEX5 Antibody (aa179-228) - LS-C111799 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PEX5 antibody LS-C111799 Western blot of ACHN lysate.

Anti-PEX5 Antibody - LS-C155393 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded U87 xenograft, using PEX5 antibody at 1:500 dilution.

Anti-PEX5 Antibody (clone 6G8) - LS-C115395 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6G8
Anti-PEX5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PEX5.

Anti-PEX5 Antibody - LS-C334286 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using PEX5 antibody.

Anti-PEX5 Antibody (clone 6C4) - LS-C115379 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6C4
Anti-PEX5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PEX5.

Anti-PEX5 Antibody (clone 6E9) - LS-C115417 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6E9
Anti-PEX5 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PEX5.

PEX5 Antibody - NBP2-38443 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PEX5 Antibody [NBP2-38443] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human Plasma. Lane 5: Human liver tissue

PEX5 Antibody - NBP1-87185 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PEX5 Antibody [NBP1-87185] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp

PEX5 Antibody - NBP1-54597 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PEX5 Antibody [NBP1-54597] - COLO205 cells lysate, concentration 0.2-1 ug/ml.

PEX5 Antibody - NBP1-54585 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PEX5 Antibody [NBP1-54585] - ACHN cell lysate, concentration 0.2-1 ug/ml.

PEX5 Antibody - NBP2-19781 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PEX5 Antibody [NBP2-19781] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:1000.

PEX5 Antibody - NBP1-32782 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PEX5 Antibody [NBP1-32782] - Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE, antibody diluted at 1:5000.

Anti-PEX5 antibody produced in rabbit - HPA039259 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PEX5: <B>Cat. No. HPA039259</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells of tubules.
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