| Gene Symbol |
UQCRQ
|
| Entrez Gene |
286885
|
| Alt Symbol |
QP-C
|
| Species |
Bovine
|
| Gene Type |
protein-coding
|
| Description |
ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
|
| Other Description |
complex III subunit 8|complex III subunit VIII|cytochrome b-c1 complex subunit 8|low molecular mass ubiquinone-binding protein (9.5kD)|ubiquinol-cytochrome c reductase complex 9.5 kDa protein|ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
|
| Swissprots |
Q3ZBT9 P13271
|
| Accessions |
DAA27472 P13271 BC103110 AAI03111 L06665 AAB03845 NM_174805 NP_777230
|
| Function |
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.
|
| Subcellular Location |
Mitochondrion inner membrane.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|
![Overlay histogram showing HepG2 cells stained with ab110255 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab110255, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HepG2 cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_5/18323_ab110255-2-ab110255FC.jpg)