| Gene Symbol |
FAM72A
|
| Entrez Gene |
729533
|
| Alt Symbol |
LMPIP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
family with sequence similarity 72, member A
|
| Other Description |
LMP1-induced protein|RP11-312O7.1|Ugene|latent membrane protein 1-induced protein|protein FAM72A
|
| Swissprots |
B2RV15 Q5TYM4 Q5TYM5
|
| Accessions |
CAH72364 CAH72365 CAH72366 Q5TYM5 BC035696 AAH35696 BC137545 AAI37546 BC146978 AAI46979 BC146992 AAI46993 DQ786198 XM_006711526 XP_006711589 XM_011509965 XP_011508267 XM_011509966 XP_011508268 XM_011509967 XP_011508269 NM_001123168 NP_001116640
|
| Function |
May play a role in the regulation of cellular reactive oxygen species metabolism. May participate in cell growth regulation. {ECO:0000269|PubMed:21317926}.
|
| Subcellular Location |
Cytoplasm. Mitochondrion. Note=A V5 epitope- tagged construct has been shown to localize to the nucleus (PubMed:18676834). 5-7% of total FAM72A is associated with mitochondria around the nucleus in HEK293 cells (PubMed:21317926). {ECO:0000269|PubMed:18676834, ECO:0000269|PubMed:21317926}.
|
| Tissue Specificity |
May be up-regulated in malignant colon cancers, compared to normal colon and colon adenomas. Expression is also elevated in other common cancer types, including breast, lung, uterus, and ovary. {ECO:0000269|PubMed:18676834}.
|