Gene Symbol | FAM72A |
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Entrez Gene | 729533 |
Alt Symbol | LMPIP |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 72, member A |
Other Description | LMP1-induced protein|RP11-312O7.1|Ugene|latent membrane protein 1-induced protein|protein FAM72A |
Swissprots | B2RV15 Q5TYM4 Q5TYM5 |
Accessions | CAH72364 CAH72365 CAH72366 Q5TYM5 BC035696 AAH35696 BC137545 AAI37546 BC146978 AAI46979 BC146992 AAI46993 DQ786198 XM_006711526 XP_006711589 XM_011509965 XP_011508267 XM_011509966 XP_011508268 XM_011509967 XP_011508269 NM_001123168 NP_001116640 |
Function | May play a role in the regulation of cellular reactive oxygen species metabolism. May participate in cell growth regulation. {ECO:0000269|PubMed:21317926}. |
Subcellular Location | Cytoplasm. Mitochondrion. Note=A V5 epitope- tagged construct has been shown to localize to the nucleus (PubMed:18676834). 5-7% of total FAM72A is associated with mitochondria around the nucleus in HEK293 cells (PubMed:21317926). {ECO:0000269|PubMed:18676834, ECO:0000269|PubMed:21317926}. |
Tissue Specificity | May be up-regulated in malignant colon cancers, compared to normal colon and colon adenomas. Expression is also elevated in other common cancer types, including breast, lung, uterus, and ovary. {ECO:0000269|PubMed:18676834}. |
FAM72A CRISPR/Cas9 KO Plasmid (h) - sc-409422 from Santa Cruz Biotechnology
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FAM72A HDR Plasmid (h) - sc-409422-HDR from Santa Cruz Biotechnology
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FAM72A Double Nickase Plasmid (h) - sc-409422-NIC from Santa Cruz Biotechnology
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FAM72A Double Nickase Plasmid (h2) - sc-409422-NIC-2 from Santa Cruz Biotechnology
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FAM72A CRISPR Activation Plasmid (h) - sc-409422-ACT from Santa Cruz Biotechnology
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FAM72A CRISPR Activation Plasmid (h2) - sc-409422-ACT-2 from Santa Cruz Biotechnology
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FAM72A Lentiviral Activation Particles (h) - sc-409422-LAC from Santa Cruz Biotechnology
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FAM72A Lentiviral Activation Particles (h2) - sc-409422-LAC-2 from Santa Cruz Biotechnology
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FAM72A siRNA (h) - sc-88629 from Santa Cruz Biotechnology
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FAM72A shRNA Plasmid (h) - sc-88629-SH from Santa Cruz Biotechnology
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FAM72A shRNA (h) Lentiviral Particles - sc-88629-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU127051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8392 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8392 from Sigma-Aldrich
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FAM72A siRNA (Human) - CRJ8734 from Cohesion Biosciences
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FAM72A - MBS8229805 from MyBioSource
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shRNA set against Human FAM72A (NM_001123168.1) - SHH291689 from Creative biogene
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Human FAM72A siRNA - orb279235 from Biorbyt
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FAM72A shRNA Plasmid (Human) - CHJ8734 from Cohesion Biosciences
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