Gene Symbol | PDIA2 |
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Entrez Gene | 64714 |
Alt Symbol | PDA2, PDI, PDIP, PDIR |
Species | Human |
Gene Type | protein-coding |
Description | protein disulfide isomerase family A, member 2 |
Other Description | Rho GDP dissociation inhibitor gamma|pancreas-specific protein disulfide isomerase|pancreatic protein disulfide isomerase|protein disulfide isomerase A2|protein disulfide isomerase, pancreatic|protein disulfide isomerase-associated 2|protein disulfide-isomerase A2 |
Swissprots | B4DI27 A6ZJ64 Q13087 Q9BW95 Q6B010 Q2WGM4 Q4TT67 Q96KJ6 |
Accessions | AAK61223 ABO43034 CAI95586 CAI95587 CAI95588 CAO78188 EAW85838 Q13087 AK075485 BAG52154 AK124931 BAG54115 AK295383 BAG58339 AK308516 BC000537 AAH00537 BC027964 BC075029 AAH75029 BC167826 AAI67826 DA207692 U19948 AAC50401 Z84717 NM_006849 NP_006840 |
Function | Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. {ECO:0000269|PubMed:19150607, ECO:0000269|PubMed:19429457}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. |
Tissue Specificity | Highly expressed in pancreas (at protein level). {ECO:0000269|PubMed:19429457, ECO:0000269|PubMed:8561901, ECO:0000269|PubMed:9115635}. |
PDIA2 CRISPR/Cas9 KO Plasmid (h) - sc-413019 from Santa Cruz Biotechnology
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PDIA2 HDR Plasmid (h) - sc-413019-HDR from Santa Cruz Biotechnology
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PDIA2 Double Nickase Plasmid (h) - sc-413019-NIC from Santa Cruz Biotechnology
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PDIA2 Double Nickase Plasmid (h2) - sc-413019-NIC-2 from Santa Cruz Biotechnology
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PDIA2 CRISPR Activation Plasmid (h) - sc-413019-ACT from Santa Cruz Biotechnology
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PDIA2 CRISPR Activation Plasmid (h2) - sc-413019-ACT-2 from Santa Cruz Biotechnology
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PDIA2 Lentiviral Activation Particles (h) - sc-413019-LAC from Santa Cruz Biotechnology
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PDIA2 Lentiviral Activation Particles (h2) - sc-413019-LAC-2 from Santa Cruz Biotechnology
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PDIA2 siRNA (h) - sc-93245 from Santa Cruz Biotechnology
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PDIA2 shRNA Plasmid (h) - sc-93245-SH from Santa Cruz Biotechnology
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PDIA2 shRNA (h) Lentiviral Particles - sc-93245-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU141431 from Sigma-Aldrich
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MISSION® esiRNA - EHU094801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2354 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2354 from Sigma-Aldrich
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PDIA2 siRNA (Human) - CRJ2054 from Cohesion Biosciences
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shRNA set against Human PDIA2 (NM_006849.2) - SHH372780 from Creative biogene
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shRNA set against Human PDIA2(NM_006849.2) - SHR101922 from Creative biogene
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PDIA2 shRNA Plasmid (Human) - CHJ2054 from Cohesion Biosciences
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PDIA2 miRNA 3'UTR clone - MiUTR1H-07739 from Creative biogene
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