| Gene Symbol |
TRIM38
|
| Entrez Gene |
10475
|
| Alt Symbol |
RNF15, RORET
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tripartite motif containing 38
|
| Other Description |
E3 ubiquitin-protein ligase TRIM38|Ro/SSA ribonucleoprotein homolog|ring finger protein 15|tripartite motif-containing protein 38|zinc finger protein RoRet
|
| Swissprots |
B2R862 O00635
|
| Accessions |
AAB82084 EAW55501 EAW55502 EAW55503 EAW55504 EAW55505 EAW55506 O00635 AB209906 BAD93143 AK310777 AK313248 BAG36059 BC026930 AAH26930 BX640949 CAE45973 CR936707 DA603151 DQ894918 ABM85844 EU176297 ABW03748 EU831816 ACE87334 EU831893 ACE86652 U90547 AAB53425 XM_005248799 XP_005248856 XM_005248800 XP_005248857 XM_011514232 XP_011512534 NM_006355 NP_006346
|
| Function |
E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling. {ECO:0000269|PubMed:23056470}.
|
| Tissue Specificity |
Ubiquitous.
|