Gene Symbol | TRIM38 |
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Entrez Gene | 10475 |
Alt Symbol | RNF15, RORET |
Species | Human |
Gene Type | protein-coding |
Description | tripartite motif containing 38 |
Other Description | E3 ubiquitin-protein ligase TRIM38|Ro/SSA ribonucleoprotein homolog|ring finger protein 15|tripartite motif-containing protein 38|zinc finger protein RoRet |
Swissprots | B2R862 O00635 |
Accessions | AAB82084 EAW55501 EAW55502 EAW55503 EAW55504 EAW55505 EAW55506 O00635 AB209906 BAD93143 AK310777 AK313248 BAG36059 BC026930 AAH26930 BX640949 CAE45973 CR936707 DA603151 DQ894918 ABM85844 EU176297 ABW03748 EU831816 ACE87334 EU831893 ACE86652 U90547 AAB53425 XM_005248799 XP_005248856 XM_005248800 XP_005248857 XM_011514232 XP_011512534 NM_006355 NP_006346 |
Function | E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling. {ECO:0000269|PubMed:23056470}. |
Tissue Specificity | Ubiquitous. |
TRIM38 CRISPR/Cas9 KO Plasmid (h) - sc-411476 from Santa Cruz Biotechnology
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TRIM38 HDR Plasmid (h) - sc-411476-HDR from Santa Cruz Biotechnology
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TRIM38 Double Nickase Plasmid (h) - sc-411476-NIC from Santa Cruz Biotechnology
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TRIM38 Double Nickase Plasmid (h2) - sc-411476-NIC-2 from Santa Cruz Biotechnology
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TRIM38 CRISPR Activation Plasmid (h) - sc-411476-ACT from Santa Cruz Biotechnology
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TRIM38 CRISPR Activation Plasmid (h2) - sc-411476-ACT-2 from Santa Cruz Biotechnology
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TRIM38 Lentiviral Activation Particles (h) - sc-411476-LAC from Santa Cruz Biotechnology
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TRIM38 Lentiviral Activation Particles (h2) - sc-411476-LAC-2 from Santa Cruz Biotechnology
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TRIM38 siRNA (h) - sc-95352 from Santa Cruz Biotechnology
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TRIM38 shRNA Plasmid (h) - sc-95352-SH from Santa Cruz Biotechnology
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TRIM38 shRNA (h) Lentiviral Particles - sc-95352-V from Santa Cruz Biotechnology
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TRIM38 RNAi - H00010475-R01 from Novus Biologicals
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MISSION® esiRNA - EHU075341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21976 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21976 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09289 from Sigma-Aldrich
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TRIM38 siRNA (Human) - CRH7112 from Cohesion Biosciences
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TRIM38 - MBS8217208 from MyBioSource
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shRNA set against Human TRIM38 (NM_006355.3) - SHH434690 from Creative biogene
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Human TRIM38 siRNA - orb267614 from Biorbyt
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TRIM38 shRNA Plasmid (Human) - CHH7112 from Cohesion Biosciences
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TRIM38 miRNA 3'UTR clone - MiUTR3H-16420 from Creative biogene
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