Gene Symbol |
EMCN
|
Entrez Gene |
51705
|
Alt Symbol |
EMCN2, MUC14
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
endomucin
|
Other Description |
MUC-14|endomucin-2|gastric cancer antigen Ga34|mucin-14
|
Swissprots |
Q8NEY5 Q9NRM8 Q8WWE7 B4E347 A8K716 Q9ULC0
|
Accessions |
AAY41011 CAJ01219 EAX06121 EAX06122 Q9ULC0 AB034695 BAA86228 AF205940 AAF76295 AK026875 AK222741 BAD96461 AK291831 BAF84520 AK304568 BAG65359 AK313504 BAG36284 AL133118 AY039241 AAK68660 BC017781 AAH17781 BG506923 XM_011532024 XP_011530326 NM_001159694 NP_001153166 NM_016242 NP_057326
|
Function |
Endothelial sialomucin, also called endomucin or mucin- like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
|
Subcellular Location |
Isoform 1: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note=Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.
|
Tissue Specificity |
Expressed in heart, kidney and lung. {ECO:0000269|PubMed:11418125, ECO:0000269|PubMed:12485444}.
|