Gene Symbol | EMCN |
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Entrez Gene | 51705 |
Alt Symbol | EMCN2, MUC14 |
Species | Human |
Gene Type | protein-coding |
Description | endomucin |
Other Description | MUC-14|endomucin-2|gastric cancer antigen Ga34|mucin-14 |
Swissprots | Q8NEY5 Q9NRM8 Q8WWE7 B4E347 A8K716 Q9ULC0 |
Accessions | AAY41011 CAJ01219 EAX06121 EAX06122 Q9ULC0 AB034695 BAA86228 AF205940 AAF76295 AK026875 AK222741 BAD96461 AK291831 BAF84520 AK304568 BAG65359 AK313504 BAG36284 AL133118 AY039241 AAK68660 BC017781 AAH17781 BG506923 XM_011532024 XP_011530326 NM_001159694 NP_001153166 NM_016242 NP_057326 |
Function | Endothelial sialomucin, also called endomucin or mucin- like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note=Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks. |
Tissue Specificity | Expressed in heart, kidney and lung. {ECO:0000269|PubMed:11418125, ECO:0000269|PubMed:12485444}. |
Endomucin CRISPR/Cas9 KO Plasmid (h) - sc-403680 from Santa Cruz Biotechnology
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Endomucin HDR Plasmid (h) - sc-403680-HDR from Santa Cruz Biotechnology
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Endomucin Double Nickase Plasmid (h) - sc-403680-NIC from Santa Cruz Biotechnology
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Endomucin Double Nickase Plasmid (h2) - sc-403680-NIC-2 from Santa Cruz Biotechnology
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Endomucin CRISPR Activation Plasmid (h) - sc-403680-ACT from Santa Cruz Biotechnology
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Endomucin CRISPR Activation Plasmid (h2) - sc-403680-ACT-2 from Santa Cruz Biotechnology
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Endomucin Lentiviral Activation Particles (h) - sc-403680-LAC from Santa Cruz Biotechnology
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Endomucin Lentiviral Activation Particles (h2) - sc-403680-LAC-2 from Santa Cruz Biotechnology
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Endomucin siRNA (h) - sc-43156 from Santa Cruz Biotechnology
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Endomucin shRNA Plasmid (h) - sc-43156-SH from Santa Cruz Biotechnology
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Endomucin shRNA (h) Lentiviral Particles - sc-43156-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU021931 from Sigma-Aldrich
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MISSION® esiRNA - EHU099551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7834 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7834 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04483 from Sigma-Aldrich
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EMCN siRNA (Human) - CRH9911 from Cohesion Biosciences
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EMCN - MBS8219007 from MyBioSource
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shRNA set against Human EMCN (NM_016242.3) - SHH285389 from Creative biogene
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Human EMCN siRNA - orb270413 from Biorbyt
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EMCN shRNA Plasmid (Human) - CHH9911 from Cohesion Biosciences
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EMCN miRNA 3'UTR clone - MiUTR4H-TG03067 from Creative biogene
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