NLGN3

Gene Symbol NLGN3
Entrez Gene 54413
Alt Symbol HNL3
Species Human
Gene Type protein-coding
Description neuroligin 3
Other Description gliotactin homolog|neuroligin-3
Swissprots Q8NCD0 Q9NZ97 B2RBK1 Q9NZ96 Q9P248 D2X2H6 Q9NZ94 D3DVV0 Q86V51 D3DVV1 Q9NZ95
Accessions AAF71232 AAF71233 EAX05307 EAX05308 EAX05309 EAX05310 EAX05311 EAX05312 EAX05313 Q9NZ94 AB040913 BAA96004 AF217411 AAF71230 AF217412 AAF71231 AK074814 BAC11226 AK296217 BAH12284 AK299567 BAH13067 AK299669 BAH13096 AK314699 BAG37248 BC028738 AAH28738 BC051715 AAH51715 BP201014 BX641059 CAE46030 GQ489207 ADB12634 JF432393 ADZ15610 KJ534889 AHW56529 KJ534890 AHW56530 KJ534891 AHW56531 KJ534977 AHW56617 KJ535034 AHW56673 KJ535040 AHW56679 XM_005262279 XP_005262336 XM_006724662 XP_006724725 XM_006724663 XP_006724726 XM_011530974 XP_011529276 XM_011530975 XP_011529277 NM_001166660 NP_001160132 NM_018977 NP_061850 NM_181303 NP_851820
Function Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Detected at both glutamatergic and GABAergic synapses. {ECO:0000250}.
Tissue Specificity Expressed in the blood vessel walls (at protein level). Detected in throughout the brain and in spinal cord. Detected in brain, and at lower levels in pancreas islet beta cells. {ECO:0000269|PubMed:10767552, ECO:0000269|PubMed:18755801, ECO:0000269|PubMed:19926856}.
Top Pathways Cell adhesion molecules (CAMs)

Human Neuroligin 3 full length protein - ab132403 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132403 stained with Coomassie Blue.

Human Neuroligin 3 protein fragment - ab162733 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162733 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human Neuroligin 3 protein fragment - ab200490 from Abcam

Category Protein
Source HEK 293 cells
Species Human
DTT-reduced SDS-PAGE analysis of ab200490 stained overnight with Coomassie Blue. DTT-reduced protein migrates as 100-116 kDa in SDS-PAGE due to glycosylation.

Mouse Neuroligin 3 peptide - ab34121 from Abcam

Category Peptide

NLGN3 / Neuroligin 3 Antibody Blocking Peptide - LS-E17832 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NLGN3 / Neuroligin 3 Antibody Blocking Peptide - LS-E26547 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Neuroligin 3/NLGN3 Recombinant Protein - H00054413-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Neuroligin 3/NLGN3 Partial Recombinant Protein - H00054413-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Neuroligin 3 blocking peptide - GTX88872-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Dog, Rat

Human NLGN3 His tag protein - orb84120 from Biorbyt

Category Protein
Prices $417.00, $859.00
Sizes 20 μg, 100 μg
Source Human
Species Human
SDS-PAGE analysis of Human NLGN3 His tag protein

NLGN3 Immunizing peptide - orb50369 from Biorbyt

Category Peptide
Prices $247.00
Sizes 100 μg
Species Human, Mouse, Rat

Neuroligin 3 Blocking Peptide - abx161179 from Abbexa

Category Peptide
Species Human, Mouse, Rat, Chicken, Monkey

Neuroligin 3 Peptide - AC21-1385-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

NLGN3 - H00054413-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

NLGN3 - H00054413-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

NLGN3 - H00054413-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

NLGN3 - H00054413-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Neuroligin 3 Peptide - 45-958P from ProSci

Category Peptide
Species Human

Neuroligin 3 Recombinant Protein - 96-558 from ProSci

Category Protein
Prices $450.00
Sizes 100 µg
Source HEK293 cells
Species Human
The purity of rh NLGN3 / Neuroligin-3 was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

Recombinant Human NLGN3, His tagged - NLGN3-3881H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Human Neuroligin-3 Recombinant - RKQ9NZ94 from Reprokine

Category Protein
Prices $160.00, $480.00, $1,950.00
Sizes 20 µg, 100 µg, 500 µg
Source Optimized DNA sequence encoding I extracellular domain of Human Neuroligin-3 (NL3 ) (GLN38- SER689 )including a C-terminal His tag was expressed in HEK293 cells.
Species Human

Human Neuroligin-3 / NLGN3 Protein (His Tag) - 11160-H08H-20 from Sino Biological

Category Protein
Prices $138.00, $348.00
Sizes 20 µg, 20 µg
Source Human Cells
Species Human

Neuroligin 3 Blocking Peptide - CBP3678 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Bovine, Monkey

Human Neuroligin 3 / NLGN3 Protein - NL3-H52H6 from ACROBiosystems

Category Protein
Prices $315.00, $1,800.00
Sizes 100 µg, 1 mg
Source Recombinant Human NLGN3 /Neuroligin 3 Protein (rh NLGN3 / Neuroligin-3) Gln 38 - Ser 689 (Accession # AAH51715) was produced in human 293 cells (HEK293) at ACROBiosystems.
Species Human

Recombinant Human Neuroligin-3(NLGN3) - CSB-YP873703HU CSB-EP873703HU CSB-BP873703HU CSB-MP873703HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human
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