| Gene Symbol |
TSN
|
| Entrez Gene |
7247
|
| Alt Symbol |
BCLF-1, C3PO, RCHF1, REHF-1, TBRBP, TRSLN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
translin
|
| Other Description |
component 3 of promoter of RISC|recombination hotspot associated factor|recombination hotspot-binding protein|testis brain-RNA binding protein
|
| Swissprots |
Q15631 Q5U0K7 B7Z3X8
|
| Accessions |
AAY14831 CAA73150 EAW95262 EAW95263 Q15631 AK091915 BAG52440 AK222868 BAD96588 AK296469 BAH12364 AK298812 BAH12875 AK307344 AK311410 AK315763 AL122099 BC002359 AAH02359 BP289175 BP309328 BT019490 AAV38297 BT019491 AAV38298 DA523145 DA772798 X78627 CAA55341 X95076 NM_001261401 NP_001248330 NM_004622 NP_004613 NR_048556 NR_048557 NR_048558 NR_048559
|
| Function |
DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:11801738}. Nucleus {ECO:0000269|PubMed:11801738}.
|