Gene Symbol | JAKMIP1 |
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Entrez Gene | 152789 |
Alt Symbol | Gababrbp, JAMIP1, MARLIN1 |
Species | Human |
Gene Type | protein-coding |
Description | janus kinase and microtubule interacting protein 1 |
Other Description | GABA-B receptor-binding protein|Jak and microtubule interacting protein 1|janus kinase and microtubule-interacting protein 1|marlin-1|multiple alpha-helices and RNA-linker protein 1|multiple coiled-coil GABABR1-binding protein |
Swissprots | A6H2J4 A6H2J5 Q8N7G3 Q96N16 A6H2J2 Q86Y69 B8ZZR7 D3DVT0 A8MTK6 A6H2J3 B4DHZ8 |
Accessions | EAW82401 EAW82402 Q96N16 AK056126 BAB71098 AK098536 BAC05325 AK124718 BAG54078 AK294356 BAG57621 AK295339 BAG58310 AK307983 AM412307 CAL80778 AM412308 CAL80779 AM412309 CAL80780 AM412310 CAL80781 AW157571 AY382340 AAR26235 BC026343 BC047075 AAH47075 BM714077 DA155551 JF432338 ADZ15555 XM_011513399 XP_011511701 XM_011513400 XP_011511702 XM_011513401 XP_011511703 NM_001099433 NP_001092903 NM_001306133 NP_001293062 NM_001306134 NP_001293063 NM_144720 NP_653321 |
Function | Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. {ECO:0000269|PubMed:14718537, ECO:0000269|PubMed:15277531, ECO:0000269|PubMed:17532644}. |
Subcellular Location | Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells. |
Tissue Specificity | Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine. {ECO:0000269|PubMed:15277531, ECO:0000269|PubMed:17761393}. |
Human JAKMIP1 protein fragment - ab127233 from Abcam
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JAKMIP1 Antibody Blocking Peptide - LS-E31378 from LifeSpan Bioscience
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JAKMIP1 Antibody Blocking Peptide - LS-E9721 from LifeSpan Bioscience
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JAKMIP1 Antibody Blocking Peptide - LS-E15102 from LifeSpan Bioscience
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JAKMIP1 Antibody Blocking Peptide - LS-E15101 from LifeSpan Bioscience
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JAKMIP1-Antibody-Center-Blocking-Peptide - BP8685c from Abgent, a WuXi AppTec company
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JAKMIP1 Blocking Peptide - 33R-2981 from Fitzgerald
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JAKMIP1 Peptide - 7165P from ProSci
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JAKMIP1 fusion protein - Ag4816 from Proteintech Group
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JAKMIP1 fusion protein - ag4999 from Proteintech Group
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Recombinant Human JAKMIP1, GST-tagged - JAKMIP1-200H from Creative Biomart
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Recombinant Human Janus kinase and microtubule-interacting protein 1(JAKMIP1) - CSB-YP853468HU CSB-EP853468HU CSB-BP853468HU CSB-MP853468HU from Cusabio
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JAKMIP1 Recombinant Protein Antigen - NBP2-14137PEP from Novus Biologicals
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JAKMIP1 Peptide, Human - M34GP07852H from Creative Peptides
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Janus kinase and microtubule-interacting protein 1 (JAKMIP1), Recombinant Protein - MBS1289111 from MyBioSource
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