Gene Symbol | FLG |
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Entrez Gene | 2312 |
Alt Symbol | ATOD2 |
Species | Human |
Gene Type | protein-coding |
Description | filaggrin |
Other Description | epidermal filaggrin |
Swissprots | P20930 Q01720 Q5T583 Q9UC71 |
Accessions | AAA36487 AAA60177 AAA63243 AAA63244 AAC23559 AFH55054 AFH55055 AFH55056 AFH55057 AFH55058 AFH55059 CAP07487 CAP11455 CAR97069 CAT82291 CCQ43164 EAW53383 EAW53384 EAW53385 P20930 AB208881 BAD92118 GU014833 ACX32320 L01090 AAA60176 M24355 AAA52454 M60495 AAA63245 M60499 AAA63246 M60500 AAA63247 M60502 AAA63248 XM_011509329 XP_011507631 NM_002016 NP_002007 |
Function | Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. |
Tissue Specificity | Keratohyalin granules. {ECO:0000269|PubMed:1429717}. |
Filaggrin CRISPR/Cas9 KO Plasmid (h) - sc-400644 from Santa Cruz Biotechnology
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Filaggrin HDR Plasmid (h) - sc-400644-HDR from Santa Cruz Biotechnology
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Filaggrin Double Nickase Plasmid (h) - sc-400644-NIC from Santa Cruz Biotechnology
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Filaggrin Double Nickase Plasmid (h2) - sc-400644-NIC-2 from Santa Cruz Biotechnology
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Filaggrin CRISPR Activation Plasmid (h) - sc-400644-ACT from Santa Cruz Biotechnology
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Filaggrin CRISPR Activation Plasmid (h2) - sc-400644-ACT-2 from Santa Cruz Biotechnology
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Filaggrin Lentiviral Activation Particles (h) - sc-400644-LAC from Santa Cruz Biotechnology
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Filaggrin Lentiviral Activation Particles (h2) - sc-400644-LAC-2 from Santa Cruz Biotechnology
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Filaggrin siRNA (h) - sc-43364 from Santa Cruz Biotechnology
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Filaggrin shRNA Plasmid (h) - sc-43364-SH from Santa Cruz Biotechnology
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Filaggrin shRNA (h) Lentiviral Particles - sc-43364-V from Santa Cruz Biotechnology
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Filaggrin RNAi - H00002312-R01 from Novus Biologicals
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MISSION® esiRNA - EHU030861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8729 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8729 from Sigma-Aldrich
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FLG siRNA (Human) - CRH1617 from Cohesion Biosciences
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FLG - MBS8238028 from MyBioSource
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Filaggrin CRISPR/Cas9 KO Plasmid (h2) - sc-400644-KO-2 from Santa Cruz Biotechnology
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Filaggrin HDR Plasmid (h2) - sc-400644-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human FLG (NM_002016.1) - SHH295397 from Creative biogene
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Human FLG siRNA - orb262119 from Biorbyt
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FLG shRNA Plasmid (Human) - CHH1617 from Cohesion Biosciences
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FLG miRNA 3'UTR clone - MiUTR1H-03670 from Creative biogene
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