FLG

Gene Symbol FLG
Entrez Gene 2312
Alt Symbol ATOD2
Species Human
Gene Type protein-coding
Description filaggrin
Other Description epidermal filaggrin
Swissprots P20930 Q01720 Q5T583 Q9UC71
Accessions AAA36487 AAA60177 AAA63243 AAA63244 AAC23559 AFH55054 AFH55055 AFH55056 AFH55057 AFH55058 AFH55059 CAP07487 CAP11455 CAR97069 CAT82291 CCQ43164 EAW53383 EAW53384 EAW53385 P20930 AB208881 BAD92118 GU014833 ACX32320 L01090 AAA60176 M24355 AAA52454 M60495 AAA63245 M60499 AAA63246 M60500 AAA63247 M60502 AAA63248 XM_011509329 XP_011507631 NM_002016 NP_002007
Function Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.
Tissue Specificity Keratohyalin granules. {ECO:0000269|PubMed:1429717}.

Filaggrin (H-300) - sc-30229 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Filaggrin (H-300): sc-30229. Western blot analysis of Filaggrin expression in U-251-MG whole cell lysate (A) and human skin tissue extract (B).

Filaggrin (G-20) - sc-25897 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Filaggrin (AE21) - sc-80609 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Filaggrin (AE21): sc-80609. Immunoperoxidase staining of formalin fixed, paraffin-embedded human vulva and anal skin tissue showing cytoplasmic staining of epidermal cells.

Filaggrin (AKH1) - sc-66192 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Filaggrin (N-20) - sc-25896 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Filaggrin (N-20): sc-25896. Immunoperoxidase staining of formalin fixed, paraffin-embedded human vulva/anal skin tissue showing cytoplasmic staining of epidermal cells.

Anti-Filaggrin antibody - ab24584 from Abcam

Prices $390.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab24584 stained human HeLa cells. The cells were methanol fixed (5 min) and incubated with the antibody (ab24584, 1µg/ml) for 1h at room temperature. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Image-iTTM FX Signal Enhancer was used as the primary blocking agent, 5% BSA (in TBS-T) was used for all other blocking steps. DAPI was used to stain the cell nuclei (blue). Alexa Fluor® 594 WGA was used to label plasma membranes (red).

Anti-Filaggrin antibody - ab81468 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab81468 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab81468, 1/1000 dilution) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h.Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Filaggrin antibody [FLG01] - ab3137 from Abcam

Prices $382.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone FLG01
Overlay histogram showing A431 cells stained with ab3137 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab3137, 1µg/1x106 cells) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed. This antibody gave a positive signal in A431 cells fixed with 100% methanol (5 min)/permeabilized in 0.1% PBS-Tween used under the same conditions.

Anti-Filaggrin antibody [SPM181] - ab17808 from Abcam

Prices $392.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone SPM181
ab17808 staining Filaggrin in Human skin tissue sections by Immunohistochemistry (IHC-P - paraffin-embedded sections). Tissue was fixed with 10% NBF and blocked with 0.025% serum free protein block for 5 minutes at 25°C; antigen retrieval was by heat mediation with a TRIS/EDTA buffer (pH9). Samples were incubated with primary antibody (1/50 in serum free antibody diluent) for 30 minutes at 25°C. An undiluted HRP-conjugated Goat polymer was used as the secondary antibody.See Abreview

Anti-Filaggrin antibody [SPM181], prediluted - ab18098 from Abcam

Host Mouse
Clonality Monoclonal
Clone SPM181
ab18098 staining human Filaggrin in human skin by Immunohistochemistry (FFPE-sections).

Anti-FLG / Filaggrin Antibody (N-Terminus) - LS-C145008 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody (N-Terminus) - LS-C153448 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody (N-Terminus, clone 568) - LS-C189536 from LifeSpan Bioscience

Prices $650.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone 568

Anti-FLG / Filaggrin Antibody (N-Terminus, clone 15C10) - LS-C121213 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 15C10

Anti-FLG / Filaggrin Antibody (aa3905-4031, Biotin) - LS-C297832 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody (clone FLG01, Azide-free) - LS-C88186 from LifeSpan Bioscience

Prices $620.00, $925.00
Sizes 100 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone FLG01

Anti-FLG / Filaggrin Antibody (aa119-336, Biotin) - LS-C297061 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody (aa3905-4031, FITC) - LS-C301344 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody (aa119-336, FITC) - LS-C302605 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody - LS-C314074 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody (HRP) - LS-C318625 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody - LS-C318626 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody (FITC) - LS-C318628 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody (Biotin) - LS-C319047 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FLG / Filaggrin Antibody (clone FLG01) - LS-C88185 from LifeSpan Bioscience

Prices $280.00, $555.00, $850.00
Sizes 100 µl, 500 µl, 1 ml
Host Mouse
Clonality Monoclonal
Clone FLG01
Formalin-fixed, paraffin-embedded human skin stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of keratinized epithelial cells of hair follicle.
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