Gene Symbol |
DUSP2
|
Entrez Gene |
1844
|
Alt Symbol |
PAC-1, PAC1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
dual specificity phosphatase 2
|
Other Description |
dual specificity protein phosphatase 2|dual specificity protein phosphatase PAC-1|dual-specificity phosphatase 2|serine/threonine specific protein phosphatase
|
Swissprots |
Q05923 Q53T45
|
Accessions |
AAA86112 AAY24222 EAW71384 EAW71385 EAW71386 EAW71387 EAW71388 Q05923 AF331843 AAL57044 BC007771 AAH07771 DB475178 EU832639 ACE87730 EU832716 ACE87048 L11329 AAA50779 NM_004418 NP_004409
|
Function |
Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
|
Subcellular Location |
Nucleus.
|
Tissue Specificity |
Expressed in hematopoietic tissues.
|
Top Pathways |
MAPK signaling pathway
|