Gene Symbol | DUSP2 |
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Entrez Gene | 1844 |
Alt Symbol | PAC-1, PAC1 |
Species | Human |
Gene Type | protein-coding |
Description | dual specificity phosphatase 2 |
Other Description | dual specificity protein phosphatase 2|dual specificity protein phosphatase PAC-1|dual-specificity phosphatase 2|serine/threonine specific protein phosphatase |
Swissprots | Q05923 Q53T45 |
Accessions | AAA86112 AAY24222 EAW71384 EAW71385 EAW71386 EAW71387 EAW71388 Q05923 AF331843 AAL57044 BC007771 AAH07771 DB475178 EU832639 ACE87730 EU832716 ACE87048 L11329 AAA50779 NM_004418 NP_004409 |
Function | Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed in hematopoietic tissues. |
Top Pathways | MAPK signaling pathway |
PAC-1 CRISPR/Cas9 KO Plasmid (h) - sc-401917 from Santa Cruz Biotechnology
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PAC-1 HDR Plasmid (h) - sc-401917-HDR from Santa Cruz Biotechnology
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PAC-1 Double Nickase Plasmid (h) - sc-401917-NIC from Santa Cruz Biotechnology
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PAC-1 Double Nickase Plasmid (h2) - sc-401917-NIC-2 from Santa Cruz Biotechnology
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PAC-1 CRISPR Activation Plasmid (h) - sc-401917-ACT from Santa Cruz Biotechnology
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PAC-1 CRISPR Activation Plasmid (h2) - sc-401917-ACT-2 from Santa Cruz Biotechnology
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PAC-1 Lentiviral Activation Particles (h) - sc-401917-LAC from Santa Cruz Biotechnology
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PAC-1 Lentiviral Activation Particles (h2) - sc-401917-LAC-2 from Santa Cruz Biotechnology
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PAC-1 siRNA (h) - sc-39004 from Santa Cruz Biotechnology
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PAC-1 shRNA Plasmid (h) - sc-39004-SH from Santa Cruz Biotechnology
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PAC-1 shRNA (h) Lentiviral Particles - sc-39004-V from Santa Cruz Biotechnology
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DUSP2 RNAi - H00001844-R01 from Novus Biologicals
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MISSION® esiRNA - EHU118691 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0118 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0120 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0119 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7551 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05101 from Sigma-Aldrich
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DUSP2 siRNA (Human) - CRH1292 from Cohesion Biosciences
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DUSP2 - MBS8233062 from MyBioSource
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DUSP2 shRNA Plasmid (Human) - CHH1292 from Cohesion Biosciences
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DUSP2 miRNA 3'UTR clone - MiUTR3H-05618 from Creative biogene
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