Gene Symbol |
Ggcx
|
Entrez Gene |
81716
|
Alt Symbol |
-
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
gamma-glutamyl carboxylase
|
Other Description |
peptidyl-glutamate 4-carboxylase|vitamin K gamma glutamyl carboxylase|vitamin K-dependent gamma-carboxylase
|
Swissprots |
O88496
|
Accessions |
EDL91036 EDL91037 EDL91038 O88496 AF065387 AAC82374 BC060553 AAH60553 BC100621 AAI00622 BC168647 AAI68647 NM_031756 NP_113944
|
Function |
Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Top Pathways |
Ubiquinone and other terpenoid-quinone biosynthesis
|