Gene Symbol | Ggcx |
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Entrez Gene | 81716 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | gamma-glutamyl carboxylase |
Other Description | peptidyl-glutamate 4-carboxylase|vitamin K gamma glutamyl carboxylase|vitamin K-dependent gamma-carboxylase |
Swissprots | O88496 |
Accessions | EDL91036 EDL91037 EDL91038 O88496 AF065387 AAC82374 BC060553 AAH60553 BC100621 AAI00622 BC168647 AAI68647 NM_031756 NP_113944 |
Function | Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis |
CompoZr® Knockout ZFN Kit - CKOZFN54402 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND54402 from Sigma-Aldrich
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GGCX siRNA (Rat) - CRR2315 from Cohesion Biosciences
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GGCX - MBS8238626 from MyBioSource
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shRNA set against Rat GGCX (NM_031756.1) - SHH300790 from Creative biogene
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shRNA set against Rat Ggcx(NM_031756.1) - SHH083081 from Creative biogene
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Rat GGCX siRNA - orb297164 from Biorbyt
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GGCX shRNA Plasmid (Rat) - CHR2315 from Cohesion Biosciences
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GGCX miRNA 3'UTR clone - MiUTR1R-02088 from Creative biogene
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