| Gene Symbol |
CD53
|
| Entrez Gene |
963
|
| Alt Symbol |
MOX44, TSPAN25
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CD53 molecule
|
| Other Description |
CD53 antigen|CD53 glycoprotein|CD53 tetraspan antigen|antigen MOX44 identified by monoclonal antibody MRC-OX44|cell surface antigen|cell surface glycoprotein CD53|leukocyte surface antigen CD53|tetraspanin-25|transmembrane glycoprotein|tspan-25
|
| Swissprots |
P19397 B2R905 Q5U0D6
|
| Accessions |
EAW56459 P19397 AK298723 BAG60877 AK313582 BAG36352 BC035456 BC040693 AAH40693 BG536920 BT019643 AAV38449 CA453414 M37033 AAA35663 M60871 AAA51951 XM_006711053 XP_006711116 XM_011542447 XP_011540749 NM_000560 NP_000551 NM_001040033 NP_001035122
|
| Function |
Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}. Cell junction {ECO:0000250}. Membrane; Multi-pass membrane protein. Note=Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes. {ECO:0000250}.
|
| Tissue Specificity |
B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T-cells.
|
