Gene Symbol | CD53 |
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Entrez Gene | 963 |
Alt Symbol | MOX44, TSPAN25 |
Species | Human |
Gene Type | protein-coding |
Description | CD53 molecule |
Other Description | CD53 antigen|CD53 glycoprotein|CD53 tetraspan antigen|antigen MOX44 identified by monoclonal antibody MRC-OX44|cell surface antigen|cell surface glycoprotein CD53|leukocyte surface antigen CD53|tetraspanin-25|transmembrane glycoprotein|tspan-25 |
Swissprots | P19397 B2R905 Q5U0D6 |
Accessions | EAW56459 P19397 AK298723 BAG60877 AK313582 BAG36352 BC035456 BC040693 AAH40693 BG536920 BT019643 AAV38449 CA453414 M37033 AAA35663 M60871 AAA51951 XM_006711053 XP_006711116 XM_011542447 XP_011540749 NM_000560 NP_000551 NM_001040033 NP_001035122 |
Function | Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}. Cell junction {ECO:0000250}. Membrane; Multi-pass membrane protein. Note=Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes. {ECO:0000250}. |
Tissue Specificity | B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T-cells. |
CD53 CRISPR/Cas9 KO Plasmid (h) - sc-405861 from Santa Cruz Biotechnology
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CD53 HDR Plasmid (h) - sc-405861-HDR from Santa Cruz Biotechnology
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CD53 Double Nickase Plasmid (h) - sc-405861-NIC from Santa Cruz Biotechnology
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CD53 Double Nickase Plasmid (h2) - sc-405861-NIC-2 from Santa Cruz Biotechnology
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CD53 CRISPR Activation Plasmid (h) - sc-405861-ACT from Santa Cruz Biotechnology
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CD53 CRISPR Activation Plasmid (h2) - sc-405861-ACT-2 from Santa Cruz Biotechnology
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CD53 Lentiviral Activation Particles (h) - sc-405861-LAC from Santa Cruz Biotechnology
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CD53 Lentiviral Activation Particles (h2) - sc-405861-LAC-2 from Santa Cruz Biotechnology
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CD53 siRNA (h) - sc-42796 from Santa Cruz Biotechnology
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CD53 shRNA Plasmid (h) - sc-42796-SH from Santa Cruz Biotechnology
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CD53 shRNA (h) Lentiviral Particles - sc-42796-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU048151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5737 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5737 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06159 from Sigma-Aldrich
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CD53 siRNA (Human) - CRH0685 from Cohesion Biosciences
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CD53 - MBS8211731 from MyBioSource
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shRNA set against Human CD53 (NM_000560.3) - SHH259197 from Creative biogene
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shRNA set against Human CD53(NM_000560.3) - SHG158309 from Creative biogene
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Human CD53 siRNA - orb261187 from Biorbyt
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CD53 shRNA Plasmid (Human) - CHH0685 from Cohesion Biosciences
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CD53 miRNA 3'UTR clone - MiUTR1H-01890 from Creative biogene
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CD53 miRNA 3'UTR clone - MiUTR3H-01317 from Creative biogene
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