DYM

Gene Symbol DYM
Entrez Gene 54808
Alt Symbol DMC, SMC
Species Human
Gene Type protein-coding
Description dymeclin
Other Description dyggve-Melchior-Clausen syndrome protein
Swissprots A8K5I8 Q7RTS9 B4DKI7 Q3ZTS8 Q9NPU7 Q8N2M0 B2RCF9 Q9BVE9 Q6P2P5
Accessions EAW62932 EAW62933 EAW62934 EAW62935 EAW62936 EAW62937 Q7RTS9 AK000078 BAA90931 AK074611 BAC11088 AK091256 BAG52319 AK225205 AK291303 BAF83992 AK296579 BAG59199 AK315091 BAG37556 AL390156 CAB99092 AY364250 AAQ76809 BC001252 AAH01252 BC064394 AAH64394 BK000950 DAA00396 BQ021755 DQ925676 ABL59903 XM_006722488 XP_006722551 XM_006722490 XP_006722553 XM_006722491 XP_006722554 XM_006722492 XP_006722555 XM_011526036 XP_011524338 XM_011526037 XP_011524339 XM_011526038 XP_011524340 XM_011526039 XP_011524341 XM_011526040 XP_011524342 XM_011526041 XP_011524343 XM_011526042 XP_011524344 XM_011526043 XP_011524345 NM_017653 NP_060123
Function Necessary for correct organization of Golgi apparatus. Involved in bone development. {ECO:0000269|PubMed:21280149}.
Subcellular Location Cytoplasm. Golgi apparatus. Note=Sequence analysis programs clearly predict 1 transmembrane region. However, PubMed:18996921 shows that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol.
Tissue Specificity Expressed in most embryo-fetal and adult tissues. Abundant in primary chondrocytes, osteoblasts, cerebellum, kidney, lung, stomach, heart, pancreas and fetal brain. Very low or no expression in the spleen, thymus, esophagus, bladder and thyroid gland. {ECO:0000269|PubMed:12554689, ECO:0000269|PubMed:18996921}.

Dymeclin CRISPR/Cas9 KO Plasmid (h) - sc-409275 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dymeclin HDR Plasmid (h) - sc-409275-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dymeclin Double Nickase Plasmid (h) - sc-409275-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dymeclin Double Nickase Plasmid (h2) - sc-409275-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dymeclin CRISPR Activation Plasmid (h) - sc-409275-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dymeclin CRISPR Activation Plasmid (h2) - sc-409275-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dymeclin Lentiviral Activation Particles (h) - sc-409275-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dymeclin Lentiviral Activation Particles (h2) - sc-409275-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dymeclin siRNA (h) - sc-60558 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dymeclin shRNA Plasmid (h) - sc-60558-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dymeclin shRNA (h) Lentiviral Particles - sc-60558-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DYM RNAi - H00054808-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU032771 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7581 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7581 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01348 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01348

DYM siRNA (Human) - CRJ0230 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DYM - MBS8214094 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DYM(NM_017653.3) - SHH019991 from Creative biogene

Category siRNA
Species Reactivities Human

DYM shRNA Plasmid (Human) - CHJ0230 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DYM miRNA 3'UTR clone - MiUTR1H-03053 from Creative biogene

Species Reactivities Human
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