DYM

Gene Symbol	DYM
Entrez Gene	54808
Alt Symbol	DMC, SMC
Species	Human
Gene Type	protein-coding
Description	dymeclin
Other Description	dyggve-Melchior-Clausen syndrome protein
Swissprots	A8K5I8 Q7RTS9 B4DKI7 Q3ZTS8 Q9NPU7 Q8N2M0 B2RCF9 Q9BVE9 Q6P2P5
Accessions	EAW62932 EAW62933 EAW62934 EAW62935 EAW62936 EAW62937 Q7RTS9 AK000078 BAA90931 AK074611 BAC11088 AK091256 BAG52319 AK225205 AK291303 BAF83992 AK296579 BAG59199 AK315091 BAG37556 AL390156 CAB99092 AY364250 AAQ76809 BC001252 AAH01252 BC064394 AAH64394 BK000950 DAA00396 BQ021755 DQ925676 ABL59903 XM_006722488 XP_006722551 XM_006722490 XP_006722553 XM_006722491 XP_006722554 XM_006722492 XP_006722555 XM_011526036 XP_011524338 XM_011526037 XP_011524339 XM_011526038 XP_011524340 XM_011526039 XP_011524341 XM_011526040 XP_011524342 XM_011526041 XP_011524343 XM_011526042 XP_011524344 XM_011526043 XP_011524345 NM_017653 NP_060123
Function	Necessary for correct organization of Golgi apparatus. Involved in bone development. {ECO:0000269\|PubMed:21280149}.
Subcellular Location	Cytoplasm. Golgi apparatus. Note=Sequence analysis programs clearly predict 1 transmembrane region. However, PubMed:18996921 shows that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol.
Tissue Specificity	Expressed in most embryo-fetal and adult tissues. Abundant in primary chondrocytes, osteoblasts, cerebellum, kidney, lung, stomach, heart, pancreas and fetal brain. Very low or no expression in the spleen, thymus, esophagus, bladder and thyroid gland. {ECO:0000269\|PubMed:12554689, ECO:0000269\|PubMed:18996921}.

Dymeclin (E-15) - sc-49941 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Dymeclin (E-15): sc-49941. Western blot analysis of Dymeclin expression in mouse brain tissue extract.

Dymeclin (C-18) - sc-49940 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Dymeclin (C-18): sc-49940. Western blot analysis of Dymeclin expression in non-transfected: sc-117752 (A) and human Dymeclin transfected: sc-116965 (B) 293T whole cell lysates.

Dymeclin (H-300) - sc-98428 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Dymeclin (N-15) - sc-49942 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Dymeclin (N-15): sc-49942. Western blot analysis of Dymeclin expression in non-transfected: sc-117752 (A) and human Dymeclin transfected: sc-116965 (B) 293T whole cell lysates.

Dymeclin (P-16) - sc-49943 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-Dymeclin antibody [EPR8789] - ab133685 from Abcam

Prices	$313.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR8789

Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling Dymeclin with ab133685 at 1/100 dilution.

Anti-DYM Antibody (aa546-669, Biotin) - LS-C298401 from LifeSpan Bioscience

Prices	$435.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-DYM Antibody (aa546-669, FITC) - LS-C305090 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-DYM Antibody (aa343-431) - LS-C307326 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-DYM Antibody (aa546-669) - LS-C293713 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-DYM Antibody (Internal, clone EPR8789) - LS-C154632 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR8789

IHC of paraffin-embedded human kidney tissue using anti-DYM antibody.

DYM Antibody - NBP2-13942 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: DYM Antibody [NBP2-13942] - Staining of human cell line U-251 MG shows positivity in cytoplasm.

DYM Antibody (1C2) - H00054808-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1C2

Sandwich ELISA: DYM Antibody (1C2) [H00054808-M01] - Detection limit for recombinant GST tagged DYM is approximately 1ng/ml as a capture antibody.

Dymeclin Polyclonal Antibody - bs-13037R from Bioss

Prices	$269.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

$Formalin-fixed and paraffin embedded rat brain labeled with Anti-Dymeclin Polyclonal Antibody, Unconjugated (bs-13037R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.\\n$

Dymeclin Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13037R-A350 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Dymeclin Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13037R-A488 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Dymeclin Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13037R-A555 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Dymeclin Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13037R-A647 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Dymeclin Polyclonal Antibody, Cy3 Conjugated - bs-13037R-Cy3 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Dymeclin Polyclonal Antibody, Cy5 Conjugated - bs-13037R-Cy5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Dymeclin Polyclonal Antibody, Cy5.5 Conjugated - bs-13037R-Cy5.5 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Dymeclin Polyclonal Antibody, Cy7 Conjugated - bs-13037R-Cy7 from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Dymeclin Polyclonal Antibody, FITC Conjugated - bs-13037R-FITC from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Dymeclin Polyclonal Antibody, Biotin Conjugated - bs-13037R-Biotin from Bioss

Prices	$349.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Dymeclin Polyclonal Antibody, HRP Conjugated - bs-13037R-HRP from Bioss

Prices	$369.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

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