Gene Symbol |
UPK1B
|
Entrez Gene |
7348
|
Alt Symbol |
TSPAN20, UPIB, UPK1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
uroplakin 1B
|
Other Description |
UP1b|tetraspan|tetraspanin-20|tspan-20|uroplakin Ib|uroplakin-1b
|
Swissprots |
O60753 Q9UIM2 Q9UNX6 O75841
|
Accessions |
AAC17446 EAW79577 O75841 AB002155 BAA88878 AB015234 BAA33724 AF042331 AAC77794 AF082888 AAD09401 AK225868 AK303924 BAG64852 AK313787 BAG36524 AL709739 BC012851 BC063568 AAH63568 CR457084 CAG33365 HQ448070 ADQ32551 NM_006952 NP_008883
|
Function |
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity). {ECO:0000250}.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Bladder epithelium.
|