Gene Symbol | UPK1B |
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Entrez Gene | 7348 |
Alt Symbol | TSPAN20, UPIB, UPK1 |
Species | Human |
Gene Type | protein-coding |
Description | uroplakin 1B |
Other Description | UP1b|tetraspan|tetraspanin-20|tspan-20|uroplakin Ib|uroplakin-1b |
Swissprots | O60753 Q9UIM2 Q9UNX6 O75841 |
Accessions | AAC17446 EAW79577 O75841 AB002155 BAA88878 AB015234 BAA33724 AF042331 AAC77794 AF082888 AAD09401 AK225868 AK303924 BAG64852 AK313787 BAG36524 AL709739 BC012851 BC063568 AAH63568 CR457084 CAG33365 HQ448070 ADQ32551 NM_006952 NP_008883 |
Function | Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Bladder epithelium. |
UPIb CRISPR/Cas9 KO Plasmid (h) - sc-404274 from Santa Cruz Biotechnology
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UPIb HDR Plasmid (h) - sc-404274-HDR from Santa Cruz Biotechnology
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UPIb Double Nickase Plasmid (h) - sc-404274-NIC from Santa Cruz Biotechnology
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UPIb Double Nickase Plasmid (h2) - sc-404274-NIC-2 from Santa Cruz Biotechnology
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UPIb CRISPR Activation Plasmid (h) - sc-404274-ACT from Santa Cruz Biotechnology
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UPIb CRISPR Activation Plasmid (h2) - sc-404274-ACT-2 from Santa Cruz Biotechnology
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UPIb Lentiviral Activation Particles (h) - sc-404274-LAC from Santa Cruz Biotechnology
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UPIb Lentiviral Activation Particles (h2) - sc-404274-LAC-2 from Santa Cruz Biotechnology
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UPIb siRNA (h) - sc-41092 from Santa Cruz Biotechnology
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UPIb shRNA Plasmid (h) - sc-41092-SH from Santa Cruz Biotechnology
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UPIb shRNA (h) Lentiviral Particles - sc-41092-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU001831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22521 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13111 from Sigma-Aldrich
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UPK1B siRNA (Human) - CRH5023 from Cohesion Biosciences
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Uroplakin Ib RNAi - H00007348-R01 from Novus Biologicals
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UPK1B - MBS8211677 from MyBioSource
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shRNA set against Human UPK1B (NM_006952.3) - SHH440788 from Creative biogene
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shRNA set against Human UPK1B(NM_006952.3) - SHL115758 from Creative biogene
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Human UPK1B siRNA - orb265525 from Biorbyt
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UPK1B shRNA Plasmid (Human) - CHH5023 from Cohesion Biosciences
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UPK1B miRNA 3'UTR clone - MiUTR1H-11027 from Creative biogene
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