Gene Symbol | ZFYVE26 |
---|---|
Entrez Gene | 23503 |
Alt Symbol | FYVE-CENT, SPG15 |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger, FYVE domain containing 26 |
Other Description | FYVE domain-containing centrosomal protein|spastizin|zinc finger FYVE domain-containing protein 26 |
Swissprots | O15035 Q6ZR50 Q68DT9 B1B5Y3 B4E2U3 Q7Z3I1 Q68DK2 Q6AW90 Q8N4W7 Q7Z3A4 |
Accessions | EAW80952 EAW80953 EAW80954 EAW80955 EAW80956 Q68DK2 AB002319 BAA20779 AB425197 BAG11658 AK024743 AK304428 BAG65255 AK308233 BC008927 AAH08927 BC013909 BC033235 AAH33235 BC144594 BC172413 AAI72413 BX537886 CAD97882 BX538025 CAD97971 BX648036 BX648683 CAH10379 CR749276 CAH18131 CR749365 CAH18218 XM_006720093 XP_006720156 XM_011536606 XP_011534908 XM_011536607 XP_011534909 XM_011536608 XP_011534910 XM_011536609 XP_011534911 NM_015346 NP_056161 |
Function | Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair. {ECO:0000269|PubMed:20208530}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20208530}. Midbody {ECO:0000269|PubMed:20208530}. Note=Localizes to the centrosome during all stages of the cell cycle. Recruited to the midbody during cytokinesis by KIF13A. |
Tissue Specificity | Strongest expression in the adrenal gland, bone marrow, adult brain, fetal brain, lung, placenta, prostate, skeletal muscle, testis, thymus, and retina. Intermediate levels are detected in other structures, including the spinal cord. {ECO:0000269|PubMed:18394578}. |
FYVE-CENT Antibody - 8532 from Cell Signaling Technology
|
||||||||
ZFYVE26 (C-19) - sc-79369 from Santa Cruz Biotechnology
|
||||||||
ZFYVE26 (H-300) - sc-367699 from Santa Cruz Biotechnology
|
||||||||
ZFYVE26 (N-20) - sc-79372 from Santa Cruz Biotechnology
|
||||||||
Anti-SPG15 / ZFYVE26 Antibody (C-Terminus) IHC-plus⢠- LS-B3873 from LifeSpan Bioscience
|
||||||||
Anti-SPG15 / ZFYVE26 Antibody (aa37-86) - LS-C201312 from LifeSpan Bioscience
|
||||||||
ZFYVE26 Antibody - NBP2-31606 from Novus Biologicals
|
||||||||
ZFYVE26 Antibody - NBP1-52241 from Novus Biologicals
|
||||||||
ZFYVE26 Antibody - NBP1-76331 from Novus Biologicals
|
||||||||
Anti-SPG15 antibody produced in rabbit - SAB3500005 from Sigma-Aldrich
|
||||||||
Anti-ZFYVE26 antibody produced in rabbit - HPA055500 from Sigma-Aldrich
|
||||||||
Anti-ZFYVE26 antibody produced in rabbit - SAB2900781 from Sigma-Aldrich
|
||||||||
ZFYVE26 Antibody - N-terminal region (ARP35894_P050) - ARP35894_P050 from Aviva Systems Biology
|
||||||||
SPG15 antibody - orb75145 from Biorbyt
|
||||||||
ZFYVE26 (C-term) antibody - AP26324PU-N from Acris Antibodies
|
||||||||
Rabbit Anti-Human SPG15 / ZFYVE26 (C-Terminus) - 119-13994 from RayBiotech
|
||||||||
SPG15 Antibody - 5023 from ProSci
|
||||||||
SPG15 Antibody - 254023 from ABBIOTEC
|
||||||||
SPG15 Antibody - 24839 from Signalway Antibody
|
||||||||
Anti-ZFYVE26 (C-terminal) polyclonal antibody - DPAB-DC1111 from Creative Diagnostics
|
||||||||
Anti-ZFYVE26 (C-terminal) polyclonal antibody - DPAB-L21177 from Creative Diagnostics
|
||||||||
ZFYVE26 Polyclonal Antibody - PA5-20685 from Thermo Fisher Scientific
|
||||||||
SPG15, Polyclonal Antibody - MBS150880 from MyBioSource
|
||||||||
SPG15 / ZFYVE26, Polyclonal Antibody - MBS244784 from MyBioSource
|
||||||||
SPG15 Antibody - 600-401-ET3 from Rockland Immunochemicals Inc
|