| Gene Symbol |
IMMP2L
|
| Entrez Gene |
83943
|
| Alt Symbol |
IMMP2L-IT1, IMP2, IMP2-LIKE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
|
| Other Description |
inner mitochondrial membrane peptidase 2 like|mitochondrial inner membrane protease subunit 2
|
| Swissprots |
Q96T52 Q75MP0 Q75MN9 Q96HJ2 Q75MS8 Q75MS5 Q75MF1
|
| Accessions |
AAS02043 AAS07432 AAS07496 AAS07497 AAS07528 EAL24378 EAW83444 EAW83445 EAW83446 EAW83447 Q96T52 AF359563 AAK52905 AI674788 AK311968 BAG34907 BC008497 AAH08497 BQ012840 HG500502 XM_005250630 XP_005250687 XM_011516604 XP_011514906 XM_011516605 XP_011514907 XM_011516606 XP_011514908 XM_011516607 XP_011514909 XM_011516608 XP_011514910 XM_011516609 XP_011514911 XM_011516610 XP_011514912 XM_011516611 XP_011514913 XM_011516612 XP_011514914 XM_011516613 XP_011514915 NM_001244606 NP_001231535 NM_032549 NP_115938
|
| Function |
Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. {ECO:0000269|PubMed:15814844}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000305|PubMed:15814844}; Single-pass membrane protein {ECO:0000305|PubMed:15814844}.
|
| Tissue Specificity |
Expressed in all tissues tested except adult liver and lung. {ECO:0000269|PubMed:11254443}.
|
| Top Pathways |
Protein export
|
![Western Blot: IMMP2L Overexpression Lysate (Adult Normal) [NBP2-06000] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IMMP2L.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1997_IMMP2L%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06000-img0001.jpg)