Gene Symbol | IMMP2L |
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Entrez Gene | 83943 |
Alt Symbol | IMMP2L-IT1, IMP2, IMP2-LIKE |
Species | Human |
Gene Type | protein-coding |
Description | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) |
Other Description | inner mitochondrial membrane peptidase 2 like|mitochondrial inner membrane protease subunit 2 |
Swissprots | Q96T52 Q75MP0 Q75MN9 Q96HJ2 Q75MS8 Q75MS5 Q75MF1 |
Accessions | AAS02043 AAS07432 AAS07496 AAS07497 AAS07528 EAL24378 EAW83444 EAW83445 EAW83446 EAW83447 Q96T52 AF359563 AAK52905 AI674788 AK311968 BAG34907 BC008497 AAH08497 BQ012840 HG500502 XM_005250630 XP_005250687 XM_011516604 XP_011514906 XM_011516605 XP_011514907 XM_011516606 XP_011514908 XM_011516607 XP_011514909 XM_011516608 XP_011514910 XM_011516609 XP_011514911 XM_011516610 XP_011514912 XM_011516611 XP_011514913 XM_011516612 XP_011514914 XM_011516613 XP_011514915 NM_001244606 NP_001231535 NM_032549 NP_115938 |
Function | Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. {ECO:0000269|PubMed:15814844}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000305|PubMed:15814844}; Single-pass membrane protein {ECO:0000305|PubMed:15814844}. |
Tissue Specificity | Expressed in all tissues tested except adult liver and lung. {ECO:0000269|PubMed:11254443}. |
Top Pathways | Protein export |
IMMP2L CRISPR/Cas9 KO Plasmid (h) - sc-413529 from Santa Cruz Biotechnology
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IMMP2L HDR Plasmid (h) - sc-413529-HDR from Santa Cruz Biotechnology
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IMMP2L Double Nickase Plasmid (h) - sc-413529-NIC from Santa Cruz Biotechnology
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IMMP2L Double Nickase Plasmid (h2) - sc-413529-NIC-2 from Santa Cruz Biotechnology
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IMMP2L CRISPR Activation Plasmid (h) - sc-413529-ACT from Santa Cruz Biotechnology
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IMMP2L CRISPR Activation Plasmid (h2) - sc-413529-ACT-2 from Santa Cruz Biotechnology
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IMMP2L Lentiviral Activation Particles (h) - sc-413529-LAC from Santa Cruz Biotechnology
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IMMP2L Lentiviral Activation Particles (h2) - sc-413529-LAC-2 from Santa Cruz Biotechnology
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IMMP2L siRNA (h) - sc-89651 from Santa Cruz Biotechnology
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IMMP2L shRNA Plasmid (h) - sc-89651-SH from Santa Cruz Biotechnology
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IMMP2L shRNA (h) Lentiviral Particles - sc-89651-V from Santa Cruz Biotechnology
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IMMP2L RNAi - H00083943-R01 from Novus Biologicals
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MISSION® esiRNA - EHU086271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10652 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10652 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05500 from Sigma-Aldrich
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IMMP2L siRNA (Human) - CRJ3251 from Cohesion Biosciences
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IMMP2L - MBS8219624 from MyBioSource
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shRNA set against Human IMMP2L (NM_032549.3) - SHH319249 from Creative biogene
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Human IMMP2L siRNA - orb273752 from Biorbyt
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IMMP2L shRNA Plasmid (Human) - CHJ3251 from Cohesion Biosciences
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IMMP2L miRNA 3'UTR clone - MiUTR3H-08093 from Creative biogene
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