Gene Symbol | CENPK |
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Entrez Gene | 64105 |
Alt Symbol | AF5alpha, CENP-K, FKSG14, P33, Solt |
Species | Human |
Gene Type | protein-coding |
Description | centromere protein K |
Other Description | SoxLZ/Sox6-binding protein Solt|interphase centromere complex protein 37|leucine zipper protein FKSG14|protein AF-5alpha |
Swissprots | Q9BS16 Q9H4L0 |
Accessions | EAW51353 EAW51354 Q9BS16 AF315941 AAL26880 AY009151 AAG31004 BC005400 AAH05400 BC008504 AAH08504 BG502832 DQ892541 ABM83467 DQ895752 ABM86678 XM_011543534 XP_011541836 XM_011543535 XP_011541837 XM_011543536 XP_011541838 XM_011543537 XP_011541839 XM_011543538 XP_011541840 XM_011543539 XP_011541841 XM_011543540 XP_011541842 XM_011543541 XP_011541843 XM_011543542 XP_011541844 XM_011543543 XP_011541845 XR_948282 NM_001267038 NP_001253967 NM_022145 NP_071428 |
Function | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with CASC5/KNL1 to recruit the NDC80 complex to the outer kinetochore. {ECO:0000269|PubMed:16622420, ECO:0000269|PubMed:16716197, ECO:0000269|PubMed:18045986}. |
Subcellular Location | Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex. |
Tissue Specificity | Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung and placenta. {ECO:0000269|PubMed:8950979}. |
Human FKSG14 full length protein - ab178475 from Abcam
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Human FKSG14 full length protein - ab163778 from Abcam
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Human FKSG14 protein fragment - ab163779 from Abcam
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CENPK Antibody Blocking Peptide - LS-E10062 from LifeSpan Bioscience
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Recombinant Human CENPK Protein - H00064105-Q01 from Novus Biologicals
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Recombinant Human CENPK Protein - H00064105-P01 from Novus Biologicals
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CENPK-Antibody-C-term-Blocking-Peptide - BP9316b from Abgent, a WuXi AppTec company
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CENP-K - H00064105-P01-10 from Acris Antibodies
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CENP-K - H00064105-P01-25 from Acris Antibodies
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CENP-K - H00064105-Q01-10 from Acris Antibodies
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CENP-K - H00064105-Q01-25 from Acris Antibodies
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CENPK fusion protein - Ag23823 from Proteintech Group
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CDK2 - PN201394 from Elabscience
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C1QBP74-282aa - CXY -114 from Reagent Proteins
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CDK2 1-298aa - CMB-1013 from Reagent Proteins
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Recombinant Lymphotoxin Beta (LTb) - RPB560Hu01 from Cloud-clone
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Recombinant Human Centromere protein K(CENPK) - CSB-YP005214HU CSB-EP005214HU CSB-BP005214HU CSB-MP005214HU from Cusabio
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CENPK Protein - abx164071 from Abbexa
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Centromere protein K (CENPK), Recombinant Protein - MBS1280976 from MyBioSource
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Recombinant Human CDK2/CCNE1 complex GST-His Active - CRC030A from Cell Science
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Recombinant Human CDK2/CycA Kinase Complex GST-His Active - CRC029A from Cell Science
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Recombinant Human CDK2 / p33 Protein (His tag) - PKSH031501 from Elabscience
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CENPK Peptide, Human - M34GP02971H from Creative Peptides
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CDK2 - PAT-81220-1 from Nordic BioSite
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CDK2 - PAT-81220-2 from Nordic BioSite
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