| Gene Symbol |
CENPP
|
| Entrez Gene |
401541
|
| Alt Symbol |
CENP-P
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
centromere protein P
|
| Other Description |
-
|
| Swissprots |
Q5T9F9 Q5T9F8 Q6IPU0 B3KRA5 B3KS17
|
| Accessions |
CAI84531 Q6IPU0 AK091247 BAG52317 AK092603 BAG52579 AK307262 AK307435 AL833701 BC071726 AAH71726 BX537851 CAD97859 DB056659 HQ447506 ADQ31992 XM_011518685 XP_011516987 XM_011518686 XP_011516988 XM_011518687 XP_011516989 XM_011518688 XP_011516990 XM_011518689 XP_011516991 NM_001012267 NP_001012267 NM_001286969 NP_001273898 NM_001286971 NP_001273900
|
| Function |
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. {ECO:0000269|PubMed:16622420}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:16622420}. Chromosome, centromere {ECO:0000269|PubMed:16622420}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
|
![Western Blot: CENPP Overexpression Lysate (Adult Normal) [NBL1-09091] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CENPP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10092_CENPP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09091-img0002.jpg)