Gene Symbol | CENPP |
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Entrez Gene | 401541 |
Alt Symbol | CENP-P |
Species | Human |
Gene Type | protein-coding |
Description | centromere protein P |
Other Description | - |
Swissprots | Q5T9F9 Q5T9F8 Q6IPU0 B3KRA5 B3KS17 |
Accessions | CAI84531 Q6IPU0 AK091247 BAG52317 AK092603 BAG52579 AK307262 AK307435 AL833701 BC071726 AAH71726 BX537851 CAD97859 DB056659 HQ447506 ADQ31992 XM_011518685 XP_011516987 XM_011518686 XP_011516988 XM_011518687 XP_011516989 XM_011518688 XP_011516990 XM_011518689 XP_011516991 NM_001012267 NP_001012267 NM_001286969 NP_001273898 NM_001286971 NP_001273900 |
Function | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. {ECO:0000269|PubMed:16622420}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16622420}. Chromosome, centromere {ECO:0000269|PubMed:16622420}. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex. |
CENP-P CRISPR/Cas9 KO Plasmid (h) - sc-415978 from Santa Cruz Biotechnology
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CENP-P HDR Plasmid (h) - sc-415978-HDR from Santa Cruz Biotechnology
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CENP-P Double Nickase Plasmid (h) - sc-415978-NIC from Santa Cruz Biotechnology
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CENP-P Double Nickase Plasmid (h2) - sc-415978-NIC-2 from Santa Cruz Biotechnology
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CENP-P CRISPR Activation Plasmid (h) - sc-415978-ACT from Santa Cruz Biotechnology
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CENP-P CRISPR Activation Plasmid (h2) - sc-415978-ACT-2 from Santa Cruz Biotechnology
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CENP-P Lentiviral Activation Particles (h) - sc-415978-LAC from Santa Cruz Biotechnology
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CENP-P Lentiviral Activation Particles (h2) - sc-415978-LAC-2 from Santa Cruz Biotechnology
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CENP-P siRNA (h) - sc-92769 from Santa Cruz Biotechnology
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CENP-P shRNA Plasmid (h) - sc-92769-SH from Santa Cruz Biotechnology
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CENP-P shRNA (h) Lentiviral Particles - sc-92769-V from Santa Cruz Biotechnology
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CENPP RNAi - H00401541-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN5951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5951 from Sigma-Aldrich
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CENPP siRNA (Human) - CRJ8139 from Cohesion Biosciences
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CENPP - MBS8220885 from MyBioSource
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shRNA set against Human CENPP (NM_001012267.1) - SHH261729 from Creative biogene
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shRNA set against Human CENPP(NM_001012267.1) - SHG168379 from Creative biogene
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Human CENPP siRNA - orb278640 from Biorbyt
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CENPP shRNA Plasmid (Human) - CHJ8139 from Cohesion Biosciences
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CENPP miRNA 3'UTR clone - MiUTR1H-02043 from Creative biogene
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