| Gene Symbol |
NOL3
|
| Entrez Gene |
8996
|
| Alt Symbol |
ARC, FCM, MYP, NOP, NOP30
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
| Other Description |
muscle-enriched cytoplasmic protein|nucleolar protein 3|nucleolar protein of 30 kDa
|
| Swissprots |
O60937 B4DFL0 O60936
|
| Accessions |
AAC18590 AAC18591 EAW83087 EAW83088 EAW83089 O60936 AF043244 AAC34993 AF064599 AAC18593 AF064600 AAC18594 AK092623 AK294145 BAG57471 AK314899 BAG37413 BC012798 AAH12798 BF568452 BP215200 BQ685512 BT020158 AAV38960 CB959673 DA370107 DA928396 DQ893049 ABM83975 DQ896297 ABM87296 NM_001276319 NP_001263248 XM_005256217 XP_005256274 XM_005256219 XP_005256276 XM_006721322 XP_006721385 XM_006721323 XP_006721386 XM_011523424 XP_011521726 XM_011523425 XP_011521727 XM_011523426 XP_011521728 NM_001185057 NP_001171986 NM_001276307 NP_001263236 NM_001276309 NP_001263238 NM_001276311 NP_001263240 NM_001276312 NP_001263241 NM_003946 NP_003937 NM_001185058 NP_001171987
|
| Function |
Isoform 1: May be involved in RNA splicing. {ECO:0000269|PubMed:10196175}.
|
| Subcellular Location |
Isoform 2: Cytoplasm {ECO:0000269|PubMed:10196175}. Mitochondrion {ECO:0000250|UniProtKB:Q62881}. Sarcoplasmic reticulum {ECO:0000250|UniProtKB:Q62881}. Note=Phosphorylation at Thr-149 results in translocation to mithochondria. Colocalized with mitochondria in response to oxidative stress. {ECO:0000250|UniProtKB:Q62881}.
|
| Tissue Specificity |
Highly expressed in heart and skeletal muscle. Detected at low levels in placenta, liver, kidney and pancreas.
|
![Western Blot: NOL3 Overexpression Lysate (Adult Normal) [NBL1-13710] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NOL3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5995_NOL3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13710-img0002.jpg)