| Gene Symbol |
PSMF1
|
| Entrez Gene |
9491
|
| Alt Symbol |
PI31
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
|
| Other Description |
hPI31|proteasome inhibitor PI31 subunit|proteasome inhibitor hP131 subunit
|
| Swissprots |
D3DVW3 Q9H4I1 A0AVQ9 Q92530
|
| Accessions |
EAX10649 EAX10650 EAX10651 Q92530 AA885338 AF055032 AK098612 AK294134 BAG57462 AK300667 BAG62352 AK302164 BAG63531 BC029836 BC126127 BC126462 AAI26463 BI461198 BI830805 D88378 BAA13603 DA949012 DB028624 HQ258165 ADR82919 XM_005260873 XP_005260930 XM_005260874 XP_005260931 XM_006723664 XP_006723727 NM_006814 NP_006805 NM_178578 NP_848693 NM_178579
|
| Function |
Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28. {ECO:0000269|PubMed:10764772}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:18495667}. Endoplasmic reticulum {ECO:0000269|PubMed:18495667}.
|
| Top Pathways |
Proteasome
|