CX3CL1

Gene Symbol CX3CL1
Entrez Gene 6376
Alt Symbol ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin
Species Human
Gene Type protein-coding
Description chemokine (C-X3-C motif) ligand 1
Other Description C-X3-C motif chemokine 1|CX3C membrane-anchored chemokine|fractalkine|small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)|small inducible cytokine subfamily D (Cys-X3-Cys), member-1|small-inducible cytokine D1
Swissprots P78423 O00672
Accessions AAC24307 ABK41928 EAW82919 P78423 AB209037 BAD92274 AK222692 BAD96412 AK223351 BAD97071 AK313806 BAG36542 BC001163 AAH01163 BC016164 AAH16164 CA396869 CR457426 CAG33707 DQ890704 ABM81630 DQ891871 ABM82797 DQ893888 ABM84814 DQ895059 ABM85985 GU047346 HY114023 U84487 AAB49679 U91835 AAB50014 NM_001304392 NP_001291321 NM_002996 NP_002987
Function The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. {ECO:0000269|PubMed:21829356}.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway, TNF signaling pathway

fractalkine CRISPR/Cas9 KO Plasmid (h) - sc-402339 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

fractalkine HDR Plasmid (h) - sc-402339-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

fractalkine Double Nickase Plasmid (h) - sc-402339-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

fractalkine Double Nickase Plasmid (h2) - sc-402339-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

fractalkine CRISPR Activation Plasmid (h) - sc-402339-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

fractalkine CRISPR Activation Plasmid (h2) - sc-402339-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

fractalkine Lentiviral Activation Particles (h) - sc-402339-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

fractalkine Lentiviral Activation Particles (h2) - sc-402339-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

fractalkine siRNA (h) - sc-43771 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

fractalkine shRNA Plasmid (h) - sc-43771-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

fractalkine shRNA (h) Lentiviral Particles - sc-43771-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CX3CL1/Fractalkine RNAi - H00006376-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU047751 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6792 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6792 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12807 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12807

CX3CL1 siRNA (Human) - CRH4307 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CX3CL1 - MBS8211092 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CX3CL1 (NM_002996.3) - SHH272065 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CX3CL1(NM_002996.3) - SHG212291 from Creative biogene

Category siRNA
Species Reactivities Human

CX3CL1 shRNA Plasmid (Human) - CHH4307 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CX3CL1 miRNA 3'UTR clone - MiUTR1H-02568 from Creative biogene

Species Reactivities Human
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