| Gene Symbol |
RXFP4
|
| Entrez Gene |
339403
|
| Alt Symbol |
GPCR142, GPR100, RLN3R2, RXFPR4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
relaxin/insulin-like family peptide receptor 4
|
| Other Description |
G protein-coupled receptor 100|G-protein coupled receptor 100|G-protein coupled receptor GPCR142|RLN3 receptor 2|insulin-like peptide INSL5 receptor|relaxin 3 receptor 2|relaxin family peptide receptor 4|relaxin-3 receptor 2
|
| Swissprots |
Q8NGZ8 Q3MJB1 B0M0L4 Q8TDU9
|
| Accessions |
BAB89306 BAC05844 EAW53020 Q8TDU9 AY170824 AAO17676 AY288415 AAP72124 AY394502 AAQ92316 BC101507 AAI01508 BC101509 AAI01510 DN693323 EU432129 ABY87928 NM_181885 NP_871001
|
| Function |
High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation. {ECO:0000269|PubMed:14522967, ECO:0000269|PubMed:15525639}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in a broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon. {ECO:0000269|PubMed:14530218}.
|