Gene Symbol | RXFP4 |
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Entrez Gene | 339403 |
Alt Symbol | GPCR142, GPR100, RLN3R2, RXFPR4 |
Species | Human |
Gene Type | protein-coding |
Description | relaxin/insulin-like family peptide receptor 4 |
Other Description | G protein-coupled receptor 100|G-protein coupled receptor 100|G-protein coupled receptor GPCR142|RLN3 receptor 2|insulin-like peptide INSL5 receptor|relaxin 3 receptor 2|relaxin family peptide receptor 4|relaxin-3 receptor 2 |
Swissprots | Q8NGZ8 Q3MJB1 B0M0L4 Q8TDU9 |
Accessions | BAB89306 BAC05844 EAW53020 Q8TDU9 AY170824 AAO17676 AY288415 AAP72124 AY394502 AAQ92316 BC101507 AAI01508 BC101509 AAI01510 DN693323 EU432129 ABY87928 NM_181885 NP_871001 |
Function | High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation. {ECO:0000269|PubMed:14522967, ECO:0000269|PubMed:15525639}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in a broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon. {ECO:0000269|PubMed:14530218}. |
Relaxin Receptor 4 CRISPR/Cas9 KO Plasmid (h) - sc-407601 from Santa Cruz Biotechnology
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Relaxin Receptor 4 HDR Plasmid (h) - sc-407601-HDR from Santa Cruz Biotechnology
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Relaxin Receptor 4 Double Nickase Plasmid (h) - sc-407601-NIC from Santa Cruz Biotechnology
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Relaxin Receptor 4 Double Nickase Plasmid (h2) - sc-407601-NIC-2 from Santa Cruz Biotechnology
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Relaxin Receptor 4 CRISPR Activation Plasmid (h) - sc-407601-ACT from Santa Cruz Biotechnology
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Relaxin Receptor 4 CRISPR Activation Plasmid (h2) - sc-407601-ACT-2 from Santa Cruz Biotechnology
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Relaxin Receptor 4 Lentiviral Activation Particles (h) - sc-407601-LAC from Santa Cruz Biotechnology
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Relaxin Receptor 4 Lentiviral Activation Particles (h2) - sc-407601-LAC-2 from Santa Cruz Biotechnology
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Relaxin Receptor 4 siRNA (h) - sc-60727 from Santa Cruz Biotechnology
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Relaxin Receptor 4 shRNA Plasmid (h) - sc-60727-SH from Santa Cruz Biotechnology
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Relaxin Receptor 4 shRNA (h) Lentiviral Particles - sc-60727-V from Santa Cruz Biotechnology
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RXFP4/GPCR142/GPR100 RNAi - H00339403-R02 from Novus Biologicals
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MISSION® esiRNA - EHU012111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18772 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18772 from Sigma-Aldrich
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RXFP4 siRNA (Human) - CRJ7290 from Cohesion Biosciences
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RXFP4 - MBS8241089 from MyBioSource
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shRNA set against Human RXFP4 (NM_181885.2) - SHH400964 from Creative biogene
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shRNA set against Human RXFP4(NM_181885.2) - SHR191460 from Creative biogene
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Human RXFP4 siRNA - orb277791 from Biorbyt
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RXFP4 shRNA Plasmid (Human) - CHJ7290 from Cohesion Biosciences
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RXFP4 miRNA 3'UTR clone - MiUTR1H-09095 from Creative biogene
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