Gene Symbol | ATP6V0A1 |
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Entrez Gene | 535 |
Alt Symbol | ATP6N1, ATP6N1A, Stv1, VPP1, Vph1, a1 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, H+ transporting, lysosomal V0 subunit a1 |
Other Description | ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1A (110/116kD)|ATPase, H+ transporting, lysosomal non-catalytic accessory protein 1 (110/116kD)|H(+)-transporting two-sector ATPase, 116 kDa accessory protein A1|V-ATPase 116 kDa|V-type proton ATPase 116 kDa subunit a|V-type proton ATPase 116 kDa subunit a isoform 1|clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit|vacuolar adenosine triphosphatase subunit Ac116|vacuolar proton pump subunit 1|vacuolar proton pump, subunit 1|vacuolar proton translocating ATPase 116 kDa subunit A|vacuolar-type H(+)-ATPase 115 kDa subunit |
Swissprots | Q93050 Q8N5G7 B7Z3B7 Q9NSX0 |
Accessions | EAW60830 EAW60831 Q93050 AK098213 AK125927 AK223554 BAD97274 AK294512 BAH11795 AK294789 BAH11885 AK295682 BAH12153 AK299784 BAH13127 AK316305 BAH14676 AL096733 AL137683 CAB70874 BC032398 AAH32398 BX648978 CAI56709 CR627443 CAH10528 L78933 AAL77442 U18920 AAA69700 Z71460 CAA96077 XM_005257459 XP_005257516 XM_005257461 XP_005257518 XM_005257463 XP_005257520 XM_011524908 XP_011523210 XR_934483 XR_934484 NM_001130020 NP_001123492 NM_001130021 NP_001123493 NM_005177 NP_005168 |
Function | Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasmic vesicle membrane; Multi-pass membrane protein. Melanosome. Note=Coated vesicle. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Top Pathways | Collecting duct acid secretion, Tuberculosis, Synaptic vesicle cycle, Rheumatoid arthritis, Phagosome |
V-ATPase A1 (E-8) - sc-374475 from Santa Cruz Biotechnology
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V-ATPase A1 (L-20) - sc-14756 from Santa Cruz Biotechnology
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V-ATPase A1 (H-140) - sc-28801 from Santa Cruz Biotechnology
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V-ATPase A1 (D-20) - sc-31460 from Santa Cruz Biotechnology
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V-ATPase A1 (C-16) - sc-31462 from Santa Cruz Biotechnology
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Anti-ATP6V0A1 Antibody (aa50-80, APC) - LS-C212849 from LifeSpan Bioscience
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Anti-ATP6V0A1 Antibody (aa50-80, AP) - LS-C212850 from LifeSpan Bioscience
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Anti-ATP6V0A1 Antibody (aa50-80, Biotin) - LS-C212851 from LifeSpan Bioscience
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Anti-ATP6V0A1 Antibody (aa50-80, Azide-free, HRP) - LS-C212853 from LifeSpan Bioscience
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Anti-ATP6V0A1 Antibody (aa50-80, FITC) - LS-C212852 from LifeSpan Bioscience
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Anti-ATP6V0A1 Antibody (aa671-720) - LS-C116071 from LifeSpan Bioscience
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Anti-ATP6V0A1 Antibody (aa50-80, PE) - LS-C212854 from LifeSpan Bioscience
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Anti-ATP6V0A1 Antibody (aa50-80) - LS-C319701 from LifeSpan Bioscience
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ATP6V0A1 Antibody - NBP1-59949 from Novus Biologicals
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ATP6V0A1 Antibody - NBP1-89342 from Novus Biologicals
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V-ATPase 116 kDa isoform a1 Antibody - bs-7410R from Bioss
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Anti-ATP6V0A1 antibody produced in rabbit - HPA022144 from Sigma-Aldrich
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Anti-ATP6V0A1 antibody produced in rabbit - AV46581 from Sigma-Aldrich
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ATP6V0A1 antibody - N-terminal region (ARP46581_P050) - ARP46581_P050 from Aviva Systems Biology
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ATP6V0A1-Antibody-N-term - AP5109a from Abgent, a WuXi AppTec company
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ATP6V0A1 antibody, N-term - GTX46426 from GeneTex
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Anti -ATP6V0A1, NT (ATP6V0A1, ATP6N1, ATP6N1A, VPP1, V-type proton ATPase 116kD subunit aisoform 1, Clathrin-coated vesicle/synaptic vesicle proton pump 116kD subunit, Vacuolaradenosine triphosphatase subunit Ac116, Vacuolar proton pump subunit 1, Vacuolar pr - 032291 from USBiological Life Science
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Anti -ATP6V0A1, NT (ATP6V0A1, ATP6N1, ATP6N1A, VPP1, V-type proton ATPase 116kD subunit aisoform 1, Clathrin-coated vesicle/synaptic vesicle proton pump 116kD subunit, Vacuolaradenosine triphosphatase subunit Ac116, Vacuolar proton pump subunit 1, Vacuolar pr - 032291-AP from USBiological Life Science
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Anti -ATP6V0A1, NT (ATP6V0A1, ATP6N1, ATP6N1A, VPP1, V-type proton ATPase 116kD subunit aisoform 1, Clathrin-coated vesicle/synaptic vesicle proton pump 116kD subunit, Vacuolaradenosine triphosphatase subunit Ac116, Vacuolar proton pump subunit 1, Vacuolar pr - 032291-APC from USBiological Life Science
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Anti -ATP6V0A1, NT (ATP6V0A1, ATP6N1, ATP6N1A, VPP1, V-type proton ATPase 116kD subunit aisoform 1, Clathrin-coated vesicle/synaptic vesicle proton pump 116kD subunit, Vacuolaradenosine triphosphatase subunit Ac116, Vacuolar proton pump subunit 1, Vacuolar pr - 032291-Biotin from USBiological Life Science
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