MRAS
| Gene Symbol | MRAS |
|---|---|
| Entrez Gene | 22808 |
| Alt Symbol | M-RAs, R-RAS3, RRAS3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | muscle RAS oncogene homolog |
| Other Description | muscle and microspikes RAS|ras-related protein M-Ras|ras-related protein R-Ras3 |
| Swissprots | Q86WX8 O14807 B4DIK0 |
| Accessions | EAW79068 EAW79069 EAW79070 EAW79071 O14807 AF022080 AAC52085 AF043938 AAD02287 AF493918 AAM12632 AI216578 AK056337 AK091633 AK123833 AK124954 BAG54117 AK295640 BAG58512 AK316071 BAH14442 BC017733 AAH17733 BC035939 BC047101 BC047690 BC156845 AAI56846 BI488489 BI546150 BT020057 AAV38860 CN356600 CR542067 CAG46864 DA235195 DA355883 XM_005247228 XP_005247285 XM_005247229 XP_005247286 NM_001085049 NP_001078518 NM_001252090 NP_001239019 NM_001252091 NP_001239020 NM_001252092 NP_001239021 NM_001252093 NP_001239022 NM_012219 NP_036351 |
| Function | May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway. {ECO:0000269|PubMed:16630891}. |
| Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
| Tissue Specificity | Expression highly restricted to the brain and heart. |
| Top Pathways | Tight junction, MAPK signaling pathway, HTLV-I infection, Rap1 signaling pathway, Proteoglycans in cancer |
M-Ras CRISPR/Cas9 KO Plasmid (h) - sc-405471 from Santa Cruz Biotechnology
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M-Ras HDR Plasmid (h) - sc-405471-HDR from Santa Cruz Biotechnology
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M-Ras Double Nickase Plasmid (h) - sc-405471-NIC from Santa Cruz Biotechnology
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M-Ras Double Nickase Plasmid (h2) - sc-405471-NIC-2 from Santa Cruz Biotechnology
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M-Ras CRISPR Activation Plasmid (h) - sc-405471-ACT from Santa Cruz Biotechnology
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M-Ras CRISPR Activation Plasmid (h2) - sc-405471-ACT-2 from Santa Cruz Biotechnology
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M-Ras Lentiviral Activation Particles (h) - sc-405471-LAC from Santa Cruz Biotechnology
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M-Ras Lentiviral Activation Particles (h2) - sc-405471-LAC-2 from Santa Cruz Biotechnology
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M-Ras siRNA (h) - sc-41857 from Santa Cruz Biotechnology
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M-Ras shRNA Plasmid (h) - sc-41857-SH from Santa Cruz Biotechnology
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M-Ras shRNA (h) Lentiviral Particles - sc-41857-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU063411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14524 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14524 from Sigma-Aldrich
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MRAS siRNA (Human) - CRH7785 from Cohesion Biosciences
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M-Ras/R-Ras3 RNAi - H00022808-R01 from Novus Biologicals
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shRNA set against Human MRAS (NM_012219.4) - SHH344184 from Creative biogene
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Human MRAS siRNA - orb268287 from Biorbyt
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MRAS shRNA Plasmid (Human) - CHH7785 from Cohesion Biosciences
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MRAS miRNA 3'UTR clone - MiUTR1H-06406 from Creative biogene
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MRAS miRNA 3'UTR clone - MiUTR1H-06407 from Creative biogene
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MRAS miRNA 3'UTR clone - MiUTR1H-06408 from Creative biogene
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MRAS miRNA 3'UTR clone - MiUTR1H-06409 from Creative biogene
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MRAS miRNA 3'UTR clone - MiUTR1H-06410 from Creative biogene
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