Gene Symbol |
GNG5
|
Entrez Gene |
2787
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
guanine nucleotide binding protein (G protein), gamma 5
|
Other Description |
guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
|
Swissprots |
Q5VX54 B2R5A0 P63218
|
Accessions |
AAC72203 EAW73236 P63218 AF038955 AAC39869 AF493873 AAM12587 AK312111 BAG35047 BC003563 AAH03563 BM809260 BM834854 BT006823 AAP35469 NM_005274 NP_005265
|
Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
|
Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
|
Top Pathways |
Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse
|