Gene Symbol | GNG5 |
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Entrez Gene | 2787 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), gamma 5 |
Other Description | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 |
Swissprots | Q5VX54 B2R5A0 P63218 |
Accessions | AAC72203 EAW73236 P63218 AF038955 AAC39869 AF493873 AAM12587 AK312111 BAG35047 BC003563 AAH03563 BM809260 BM834854 BT006823 AAP35469 NM_005274 NP_005265 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Top Pathways | Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse |
G γ 5 CRISPR/Cas9 KO Plasmid (h) - sc-407524 from Santa Cruz Biotechnology
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G γ 5 HDR Plasmid (h) - sc-407524-HDR from Santa Cruz Biotechnology
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G γ 5 Double Nickase Plasmid (h) - sc-407524-NIC from Santa Cruz Biotechnology
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G γ 5 Double Nickase Plasmid (h2) - sc-407524-NIC-2 from Santa Cruz Biotechnology
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G γ 5 CRISPR Activation Plasmid (h) - sc-407524-ACT from Santa Cruz Biotechnology
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G γ 5 CRISPR Activation Plasmid (h2) - sc-407524-ACT-2 from Santa Cruz Biotechnology
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G γ 5 Lentiviral Activation Particles (h) - sc-407524-LAC from Santa Cruz Biotechnology
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G γ 5 Lentiviral Activation Particles (h2) - sc-407524-LAC-2 from Santa Cruz Biotechnology
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G γ 5 siRNA (h) - sc-41778 from Santa Cruz Biotechnology
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G γ 5 shRNA Plasmid (h) - sc-41778-SH from Santa Cruz Biotechnology
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G γ 5 shRNA (h) Lentiviral Particles - sc-41778-V from Santa Cruz Biotechnology
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GNG5 RNAi - H00002787-R01 from Novus Biologicals
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MISSION® esiRNA - EHU109501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9430 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9430 from Sigma-Aldrich
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GNG5 siRNA (Human) - CRH1859 from Cohesion Biosciences
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GNG5 - MBS8224862 from MyBioSource
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Gγ 5 HDR Plasmid (h2) - sc-407524-HDR-2 from Santa Cruz Biotechnology
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Gγ 5 CRISPR/Cas9 KO Plasmid (h2) - sc-407524-KO-2 from Santa Cruz Biotechnology
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shRNA set against Human GNG5(NM_005274.2) - SHH092747 from Creative biogene
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GNG5 shRNA Plasmid (Human) - CHH1859 from Cohesion Biosciences
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GNG5 miRNA 3'UTR clone - MiUTR1H-04116 from Creative biogene
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