| Gene Symbol |
SMARCA1
|
| Entrez Gene |
6594
|
| Alt Symbol |
ISWI, NURF140, SNF2L, SNF2L1, SNF2LB, SNF2LT, SWI, SWI2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
|
| Other Description |
ATP-dependent helicase SMARCA1|SNF2-like 1|global transcription activator homologous sequence|nucleosome-remodeling factor subunit SNF2L|probable global transcription activator SNF2L1|sucrose nonfermenting 2-like protein 1
|
| Swissprots |
Q5JV42 Q5JV41 P28370
|
| Accessions |
EAX11833 EAX11834 EAX11835 EAX11836 P28370 AK026426 AK123541 AW614102 BC051825 AAH51825 BC117447 AAI17448 BC143954 AAI43955 BC143955 BQ006393 BX647934 DR002115 EU636009 ACF37172 HY043725 M89907 AAA80560 XM_005262461 XP_005262518 XM_005262462 XP_005262519 XM_006724782 XP_006724845 NM_001282874 NP_001269803 NM_001282875 NP_001269804 NM_003069 NP_003060 NM_139035
|
| Function |
Energy-transducing component of NURF (nucleosome- remodeling factor) and CERF (CECR2-containing-remodeling factor) complexes. Both complexes facilitate the perturbation of chromatin structure in an ATP-dependent manner. Potentiates neurite outgrowth. May be involved in brain development by regulating En-1 and En-2 expression. May be involved in the development of luteal cells. {ECO:0000269|PubMed:14609955, ECO:0000269|PubMed:15310751, ECO:0000269|PubMed:15640247, ECO:0000269|PubMed:16740656}.
|
| Subcellular Location |
Nucleus.
|