Gene Symbol | SMARCA1 |
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Entrez Gene | 6594 |
Alt Symbol | ISWI, NURF140, SNF2L, SNF2L1, SNF2LB, SNF2LT, SWI, SWI2 |
Species | Human |
Gene Type | protein-coding |
Description | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
Other Description | ATP-dependent helicase SMARCA1|SNF2-like 1|global transcription activator homologous sequence|nucleosome-remodeling factor subunit SNF2L|probable global transcription activator SNF2L1|sucrose nonfermenting 2-like protein 1 |
Swissprots | Q5JV42 Q5JV41 P28370 |
Accessions | EAX11833 EAX11834 EAX11835 EAX11836 P28370 AK026426 AK123541 AW614102 BC051825 AAH51825 BC117447 AAI17448 BC143954 AAI43955 BC143955 BQ006393 BX647934 DR002115 EU636009 ACF37172 HY043725 M89907 AAA80560 XM_005262461 XP_005262518 XM_005262462 XP_005262519 XM_006724782 XP_006724845 NM_001282874 NP_001269803 NM_001282875 NP_001269804 NM_003069 NP_003060 NM_139035 |
Function | Energy-transducing component of NURF (nucleosome- remodeling factor) and CERF (CECR2-containing-remodeling factor) complexes. Both complexes facilitate the perturbation of chromatin structure in an ATP-dependent manner. Potentiates neurite outgrowth. May be involved in brain development by regulating En-1 and En-2 expression. May be involved in the development of luteal cells. {ECO:0000269|PubMed:14609955, ECO:0000269|PubMed:15310751, ECO:0000269|PubMed:15640247, ECO:0000269|PubMed:16740656}. |
Subcellular Location | Nucleus. |
SNF2L CRISPR/Cas9 KO Plasmid (h) - sc-411011 from Santa Cruz Biotechnology
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SNF2L HDR Plasmid (h) - sc-411011-HDR from Santa Cruz Biotechnology
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SNF2L Double Nickase Plasmid (h) - sc-411011-NIC from Santa Cruz Biotechnology
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SNF2L Double Nickase Plasmid (h2) - sc-411011-NIC-2 from Santa Cruz Biotechnology
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SNF2L CRISPR Activation Plasmid (h) - sc-411011-ACT from Santa Cruz Biotechnology
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SNF2L CRISPR Activation Plasmid (h2) - sc-411011-ACT-2 from Santa Cruz Biotechnology
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SNF2L Lentiviral Activation Particles (h) - sc-411011-LAC from Santa Cruz Biotechnology
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SNF2L Lentiviral Activation Particles (h2) - sc-411011-LAC-2 from Santa Cruz Biotechnology
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SNF2L siRNA (h) - sc-76532 from Santa Cruz Biotechnology
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SNF2L shRNA Plasmid (h) - sc-76532-SH from Santa Cruz Biotechnology
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SNF2L shRNA (h) Lentiviral Particles - sc-76532-V from Santa Cruz Biotechnology
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SMARCA1 RNAi - H00006594-R02 from Novus Biologicals
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SMARCA1 RNAi - H00006594-R01 from Novus Biologicals
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MISSION® esiRNA - EHU134321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19760 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19760 from Sigma-Aldrich
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SMARCA1 siRNA (Human) - CRH4478 from Cohesion Biosciences
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SMARCA1 - MBS8205737 from MyBioSource
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shRNA set against Human Smarca1 (NM_003069.3) - SHH413076 from Creative biogene
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shRNA set against Human SMARCA1(NM_139035.2) - SHL015492 from Creative biogene
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SMARCA1 shRNA Plasmid (Human) - CHH4478 from Cohesion Biosciences
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SMARCA1 miRNA 3'UTR clone - MiUTR1H-09641 from Creative biogene
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SMARCA1 miRNA 3'UTR clone - MiUTR1H-09642 from Creative biogene
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