Gene Symbol |
DHODH
|
Entrez Gene |
1723
|
Alt Symbol |
DHOdehase, POADS, URA1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
dihydroorotate dehydrogenase (quinone)
|
Other Description |
dihydroorotate dehydrogenase (quinone), mitochondrial|dihydroorotate oxidase|human complement of yeast URA1
|
Swissprots |
A8K8C8 Q02127 Q6P176
|
Accessions |
EAW59198 EAW59199 EAW59200 EAW59201 Q02127 AI499306 AK097300 AK292293 BAF84982 AU130529 AU152444 BC065245 AAH65245 BE789211 BI253747 BM795077 M94065 AAA50163 XM_005255827 XP_005255884 XM_005255828 XP_005255885 XM_005255829 XP_005255886 NM_001361 NP_001352 NM_001025193
|
Function |
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
|
Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:10727948}; Single-pass membrane protein {ECO:0000269|PubMed:10727948}.
|
Top Pathways |
Pyrimidine metabolism
|