Gene Symbol | DHODH |
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Entrez Gene | 1723 |
Alt Symbol | DHOdehase, POADS, URA1 |
Species | Human |
Gene Type | protein-coding |
Description | dihydroorotate dehydrogenase (quinone) |
Other Description | dihydroorotate dehydrogenase (quinone), mitochondrial|dihydroorotate oxidase|human complement of yeast URA1 |
Swissprots | A8K8C8 Q02127 Q6P176 |
Accessions | EAW59198 EAW59199 EAW59200 EAW59201 Q02127 AI499306 AK097300 AK292293 BAF84982 AU130529 AU152444 BC065245 AAH65245 BE789211 BI253747 BM795077 M94065 AAA50163 XM_005255827 XP_005255884 XM_005255828 XP_005255885 XM_005255829 XP_005255886 NM_001361 NP_001352 NM_001025193 |
Function | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:10727948}; Single-pass membrane protein {ECO:0000269|PubMed:10727948}. |
Top Pathways | Pyrimidine metabolism |
DHODH CRISPR/Cas9 KO Plasmid (h) - sc-402983 from Santa Cruz Biotechnology
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DHODH HDR Plasmid (h) - sc-402983-HDR from Santa Cruz Biotechnology
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DHODH Double Nickase Plasmid (h) - sc-402983-NIC from Santa Cruz Biotechnology
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DHODH Double Nickase Plasmid (h2) - sc-402983-NIC-2 from Santa Cruz Biotechnology
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DHODH CRISPR Activation Plasmid (h) - sc-402983-ACT from Santa Cruz Biotechnology
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DHODH CRISPR Activation Plasmid (h2) - sc-402983-ACT-2 from Santa Cruz Biotechnology
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DHODH Lentiviral Activation Particles (h) - sc-402983-LAC from Santa Cruz Biotechnology
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DHODH Lentiviral Activation Particles (h2) - sc-402983-LAC-2 from Santa Cruz Biotechnology
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DHODH siRNA (h) - sc-77141 from Santa Cruz Biotechnology
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DHODH shRNA Plasmid (h) - sc-77141-SH from Santa Cruz Biotechnology
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DHODH shRNA (h) Lentiviral Particles - sc-77141-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU138421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1982 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1982 from Sigma-Aldrich
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DHODH siRNA (Human) - CRH1194 from Cohesion Biosciences
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DHODH RNAi - H00001723-R01 from Novus Biologicals
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DHODH - MBS8207471 from MyBioSource
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shRNA set against Human DHODH (NM_001361.4) - SHH277641 from Creative biogene
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shRNA set against Human DHODH(NM_001361.4) - SHH003665 from Creative biogene
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DHODH shRNA Plasmid (Human) - CHH1194 from Cohesion Biosciences
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DHODH miRNA 3'UTR clone - MiUTR1H-02808 from Creative biogene
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