MUC6

Gene Symbol MUC6
Entrez Gene 4588
Alt Symbol MUC-6
Species Human
Gene Type protein-coding
Description mucin 6, oligomeric mucus/gel-forming
Other Description gastric mucin-6|mucin-6
Swissprots Q8N8I1 Q4L207 Q6W4X9 Q8NAK1 Q2TUQ5 Q14394 O15329
Accessions AAQ86940 AAR14188 AAS76674 AFG72983 AFG72984 AFG72985 AFG72986 Q6W4X9 AK092533 AK096772 BAC04860 AK098503 AY312160 AAQ82434 AY458429 AAS13634 U97698 AAC51370 XM_006725532 XP_006725595 XM_011547747 XP_011546049 NM_005961 NP_005952
Function May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. {ECO:0000269|PubMed:10209489, ECO:0000269|PubMed:10330458, ECO:0000269|PubMed:11988092}.
Subcellular Location Secreted.
Tissue Specificity Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct. {ECO:0000269|PubMed:10209489, ECO:0000269|PubMed:10330458, ECO:0000269|PubMed:11988092, ECO:0000269|PubMed:15280409, ECO:0000269|PubMed:9422745}.

Mucin 6 CRISPR/Cas9 KO Plasmid (h) - sc-402946 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 6 HDR Plasmid (h) - sc-402946-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 6 Double Nickase Plasmid (h) - sc-402946-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 6 Double Nickase Plasmid (h2) - sc-402946-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 6 CRISPR Activation Plasmid (h) - sc-402946-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 6 CRISPR Activation Plasmid (h2) - sc-402946-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 6 Lentiviral Activation Particles (h) - sc-402946-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 6 Lentiviral Activation Particles (h2) - sc-402946-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 6 siRNA (h) - sc-43166 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Mucin 6 shRNA Plasmid (h) - sc-43166-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Mucin 6 shRNA (h) Lentiviral Particles - sc-43166-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU070831 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14761 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14761 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MUC6 siRNA (Human) - CRH3022 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Mucin 6 CRISPR/Cas9 KO Plasmid (h2) - sc-402946-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mucin 6 HDR Plasmid (h2) - sc-402946-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human MUC6 (NM_005961.2) - SHH346980 from Creative biogene

Category siRNA
Species Reactivities Human

Human MUC6 siRNA - orb263524 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MUC6 shRNA Plasmid (Human) - CHH3022 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MUC6 miRNA 3'UTR clone - MiUTR1H-06532 from Creative biogene

Species Reactivities Human
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