Gene Symbol | IFT122 |
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Entrez Gene | 55764 |
Alt Symbol | CED, CED1, SPG, WDR10, WDR10p, WDR140 |
Species | Human |
Gene Type | protein-coding |
Description | intraflagellar transport 122 |
Other Description | WD repeat domain 10|WD repeat-containing protein 10|WD repeat-containing protein 140|intraflagellar transport 122 homolog|intraflagellar transport protein 122 homolog |
Swissprots | Q9HAT9 G3XAB1 Q9HBG5 Q9BTY4 Q53G36 E9PDX2 H7C3C0 Q9NV68 E9PDG2 Q9HBG6 Q9UF80 E7EQF4 B4DEY9 Q8TC06 Q9BTB9 B4DPW7 B3KW53 |
Accessions | CCQ43810 EAW79245 EAW79246 EAW79247 EAW79248 EAW79249 EAW79250 Q9HBG6 AF244930 AAG15427 AF244931 AAG15428 AF302154 AAG13415 AK000773 AK001759 BAA91888 AK001955 BAA92000 AK022525 BAB14077 AK023000 BAG51146 AK024435 BAB15725 AK057162 AK093440 AK094922 BAG52955 AK096891 BAG53393 AK122965 BAG53823 AK124140 BAG54015 AK223095 BAD96815 AK293852 BAG57250 AK294515 BAG57728 AK298526 BAG60729 AK299903 BAG61744 AK307463 AK315103 AL133565 CAB63718 AL833851 CAD38710 AU123134 BC003045 AAH03045 BC004238 AAH04238 BC028353 AAH28353 BF941125 DB099554 DB516647 DC343174 DQ580537 DQ589812 EU832629 ACE87720 EU832704 ACE87036 XM_005247609 XP_005247666 XM_006713689 XP_006713752 XM_006713691 XP_006713754 XM_006713692 XP_006713755 XM_006713695 XP_006713758 XM_011512967 XP_011511269 XM_011512968 XP_011511270 XM_011512969 XP_011511271 XM_011512970 XP_011511272 XM_011512971 XP_011511273 XM_011512972 XP_011511274 XM_011512973 XP_011511275 NM_001280541 NP_001267470 NM_001280546 NP_001267475 NM_018262 NP_060732 NM_052985 NP_443711 NM_052989 NP_443715 NM_052990 NP_443716 NM_001280545 NP_001267474 |
Function | Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Cell projection, cilium {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Localizes to photoreceptor connecting cilia. {ECO:0000250}. |
Tissue Specificity | Expressed in many tissues. Predominant expression in testis and pituitary. {ECO:0000269|PubMed:11242542}. |
IFT122 (K-18) - sc-102611 from Santa Cruz Biotechnology
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IFT122 (Y-13) - sc-102612 from Santa Cruz Biotechnology
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IFT122 (E-23) - sc-133688 from Santa Cruz Biotechnology
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Anti-IFT122 antibody - ab111838 from Abcam
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Anti-IFT122 / WDR10 Antibody (aa1194-1292) - LS-C308414 from LifeSpan Bioscience
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Anti-IFT122 / WDR10 Antibody (aa819-868) - LS-C81814 from LifeSpan Bioscience
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IFT122 Antibody - NBP1-87014 from Novus Biologicals
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IFT122 Antibody - NBP2-16925 from Novus Biologicals
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IFT122 Antibody - NBP1-54842 from Novus Biologicals
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IFT122 Antibody - H00055764-A01 from Novus Biologicals
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IFT122 Antibody (3E11) - H00055764-M03 from Novus Biologicals
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IFT122 Polyclonal Antibody - bs-15558R from Bioss
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Anti-IFT122 antibody produced in rabbit - AV53817 from Sigma-Aldrich
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Anti-IFT122 antibody produced in rabbit - SAB2702110 from Sigma-Aldrich
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Monoclonal Anti-IFT122 antibody produced in mouse - SAB1401762 from Sigma-Aldrich
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Anti-IFT122 antibody produced in rabbit - HPA041815 from Sigma-Aldrich
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IFT122 antibody - C-terminal region (ARP53817_P050) - ARP53817_P050 from Aviva Systems Biology
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IFT122 antibody [C1C2], Internal - GTX119175 from GeneTex
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Anti -IFT122 (Intraflagellar Transport Protein 122 Homolog, WD Repeat-containing Protein10, WD Repeat-containing Protein 140, SPG, WDR10, WDR140) - 128321 from USBiological Life Science
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IFT122 antibody - orb157649 from Biorbyt
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IFT122 antibody - 70R-2627 from Fitzgerald
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IFT122 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15558R-A350 from Bioss
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IFT122 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15558R-A488 from Bioss
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IFT122 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15558R-A555 from Bioss
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IFT122 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15558R-A647 from Bioss
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