Gene Symbol |
UBE2R2
|
Entrez Gene |
54926
|
Alt Symbol |
CDC34B, E2-CDC34B, UBC3B
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ubiquitin-conjugating enzyme E2R 2
|
Other Description |
ubiquitin carrier protein R2|ubiquitin-conjugating enzyme E2 R2|ubiquitin-conjugating enzyme E2-CDC34B|ubiquitin-conjugating enzyme UBC3B|ubiquitin-protein ligase R2
|
Swissprots |
D3DRL5 Q9NX64 Q712K3
|
Accessions |
CCQ43572 EAW58478 EAW58479 EAW58480 Q712K3 AA397839 AJ240087 CAC80336 AK000426 BAA91156 AK225880 AL133827 AW966809 BC004862 AAH04862 BC038356 BC047584 AAH47584 BI061548 BI908167 BQ432410 CD515389 CN310827 CN427315 CR457233 CAG33514 XM_005251496 XP_005251553 XM_011517949 XP_011516251 NM_017811 NP_060281
|
Function |
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin. {ECO:0000269|PubMed:12037680, ECO:0000269|PubMed:20061386}.
|
Top Pathways |
Ubiquitin mediated proteolysis, Herpes simplex infection
|